Recombinant multi-species CRM1/XPO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRM1/XPO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]
The Alternative Names of target: CRM-1,CRM1,Chromosome region maintenance 1 protein homolog,Crm1,Exp1,Exportin-1,XPO1,Xpo1,emb,exp1,exportin-1

Target products collectionGo to CRM1/XPO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T51407-Ag-1/ GM-Tg-hg-T51407-Ag-2 Human CRM1/XPO1 protein Human
GM-Tg-rg-T51407-Ag-1/ GM-Tg-rg-T51407-Ag-2 Rat CRM1/XPO1 protein Rat
GM-Tg-mg-T51407-Ag-1/ GM-Tg-mg-T51407-Ag-2 Mouse CRM1/XPO1 protein Mouse
GM-Tg-cynog-T51407-Ag-1/ GM-Tg-cynog-T51407-Ag-2 Cynomolgus/Rhesus macaque CRM1/XPO1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T51407-Ag-1/ GM-Tg-felg-T51407-Ag-2 Feline CRM1/XPO1 protein Feline
GM-Tg-cang-T51407-Ag-1/ GM-Tg-cang-T51407-Ag-2 Canine CRM1/XPO1 protein Canine
GM-Tg-bovg-T51407-Ag-1/ GM-Tg-bovg-T51407-Ag-2 Bovine CRM1/XPO1 protein Bovine
GM-Tg-equg-T51407-Ag-1/ GM-Tg-equg-T51407-Ag-2 Equine CRM1/XPO1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T51407-Ag-1/ GM-Tg-hg-T51407-Ag-2; GM-Tg-rg-T51407-Ag-1/ GM-Tg-rg-T51407-Ag-2;
GM-Tg-mg-T51407-Ag-1/ GM-Tg-mg-T51407-Ag-2; GM-Tg-cynog-T51407-Ag-1/ GM-Tg-cynog-T51407-Ag-2;
GM-Tg-felg-T51407-Ag-1/ GM-Tg-felg-T51407-Ag-2; GM-Tg-cang-T51407-Ag-1/ GM-Tg-cang-T51407-Ag-2;
GM-Tg-bovg-T51407-Ag-1/ GM-Tg-bovg-T51407-Ag-2; GM-Tg-equg-T51407-Ag-1/ GM-Tg-equg-T51407-Ag-2
Products Name CRM1/XPO1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CRM1/XPO1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRM1/XPO1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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