Explore CRM1/XPO1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]
| Target ID |
GM-T51407
|
| Target Name |
CRM1/XPO1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7514
|
| Gene ID |
100051994 (Equus caballus), 101084532 (Felis catus), 103573 (Mus musculus), 474609 (Canis lupus familiaris)
510568 (Bos taurus), 718063 (Macaca mulatta), 7514 (Homo sapiens), 85252 (Rattus norvegicus)
|
| Target Alternative Names |
CRM-1,CRM1,Chromosome region maintenance 1 protein homolog,Crm1,Exp1,Exportin-1,XPO1,Xpo1,emb,exp1,exportin-1
|
| Uniprot Accession |
Q6P5F9,O14980,Q80U96
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Influenza A, Human T-cell leukemia virus 1 infection
|
| Gene Ensembl |
ENSECAG00000024920, ENSMUSG00000020290, ENSCAFG00845016081, ENSBTAG00000013254, ENSMMUG00000006941, ENSG00000082898
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CRM1/XPO1 cDNA Clones/ORF Plasmid
CRM1/XPO1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7514 | Pre-made Human XPO1/emb/CRM1 siRNA oligo Duplex | 7514 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo85252 | Pre-made Rat Xpo1/exp1 siRNA oligo Duplex | 85252 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo103573 | Pre-made Mouse Xpo1/Crm1/Exp1 siRNA oligo Duplex | 103573 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718063 | Pre-made Cynomolgus/Rhesus macaque XPO1/exportin-1 siRNA oligo Duplex | 718063 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084532 | Pre-made Cat/Feline XPO1 siRNA oligo Duplex | 101084532 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474609 | Pre-made Dog/Canine XPO1 siRNA oligo Duplex | 474609 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510568 | Pre-made Bovines/Cattle XPO1 siRNA oligo Duplex | 510568 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051994 | Pre-made Equine/Horse XPO1 siRNA oligo Duplex | 100051994 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CRM1/XPO1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T51407-Ab | Human | Anti-Human CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T51407-Ab | Rat | Anti-Rat CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T51407-Ab | Mouse | Anti-Mouse CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T51407-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T51407-Ab | Cat/Feline | Anti-Cat/Feline CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T51407-Ab | Dog/Canine | Anti-Dog/Canine CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T51407-Ab | Bovines/Cattle | Anti-Bovines/Cattle CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T51407-Ab | Equine/Horse | Anti-Equine/Horse CRM1/XPO1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CRM1/XPO1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T51407-Ag | Human | Human CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T51407-Ag | Rat | Rat CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T51407-Ag | Mouse | Mouse CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T51407-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T51407-Ag | Cat/Feline | Cat/Feline CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T51407-Ag | Dog/Canine | Dog/Canine CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T51407-Ag | Bovines/Cattle | Bovines/Cattle CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T51407-Ag | Equine/Horse | Equine/Horse CRM1/XPO1 recombinant protein | Mammalian cell | Detail |
