Recombinant multi-species HDAC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
The Alternative Names of target: D10Wsu179e,HD2,HDAC2,Hdac2,Histone deacetylase 2,KDAC2,Protein deacylase HDAC2,RPD3,YAF1,Yy1bp,mRPD3

Target products collectionGo to HDAC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T51191-Ag-1/ GM-Tg-hg-T51191-Ag-2 Human HDAC2 protein Human
GM-Tg-rg-T51191-Ag-1/ GM-Tg-rg-T51191-Ag-2 Rat HDAC2 protein Rat
GM-Tg-mg-T51191-Ag-1/ GM-Tg-mg-T51191-Ag-2 Mouse HDAC2 protein Mouse
GM-Tg-cynog-T51191-Ag-1/ GM-Tg-cynog-T51191-Ag-2 Cynomolgus/Rhesus macaque HDAC2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T51191-Ag-1/ GM-Tg-felg-T51191-Ag-2 Feline HDAC2 protein Feline
GM-Tg-cang-T51191-Ag-1/ GM-Tg-cang-T51191-Ag-2 Canine HDAC2 protein Canine
GM-Tg-bovg-T51191-Ag-1/ GM-Tg-bovg-T51191-Ag-2 Bovine HDAC2 protein Bovine
GM-Tg-equg-T51191-Ag-1/ GM-Tg-equg-T51191-Ag-2 Equine HDAC2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T51191-Ag-1/ GM-Tg-hg-T51191-Ag-2; GM-Tg-rg-T51191-Ag-1/ GM-Tg-rg-T51191-Ag-2;
GM-Tg-mg-T51191-Ag-1/ GM-Tg-mg-T51191-Ag-2; GM-Tg-cynog-T51191-Ag-1/ GM-Tg-cynog-T51191-Ag-2;
GM-Tg-felg-T51191-Ag-1/ GM-Tg-felg-T51191-Ag-2; GM-Tg-cang-T51191-Ag-1/ GM-Tg-cang-T51191-Ag-2;
GM-Tg-bovg-T51191-Ag-1/ GM-Tg-bovg-T51191-Ag-2; GM-Tg-equg-T51191-Ag-1/ GM-Tg-equg-T51191-Ag-2
Products Name HDAC2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HDAC2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.