Explore HDAC2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
| Target ID |
GM-T51191
|
| Target Name |
HDAC2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3066
|
| Gene ID |
100072578 (Equus caballus), 101088165 (Felis catus), 15182 (Mus musculus), 3066 (Homo sapiens)
407223 (Bos taurus), 475035 (Canis lupus familiaris), 694662 (Macaca mulatta), 84577 (Rattus norvegicus)
|
| Target Alternative Names |
D10Wsu179e,HD2,HDAC2,Hdac2,Histone deacetylase 2,KDAC2,Protein deacylase HDAC2,RPD3,YAF1,Yy1bp,mRPD3
|
| Uniprot Accession |
P70288,Q92769
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Longevity regulating pathway - multiple species, Thyroid hormone signaling pathway, Amphetamine addiction, Human papillomavirus infection, Epstein-Barr virus infection, Pathways in cancer, Chronic myeloid leukemia
|
| Gene Ensembl |
ENSECAG00000013577, ENSMUSG00000019777, ENSG00000196591, ENSBTAG00000011849, ENSCAFG00845020776, ENSMMUG00000008937
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of HDAC2 cDNA Clones/ORF Plasmid
HDAC2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3066 | Pre-made Human HDAC2/HD2/RPD3 siRNA oligo Duplex | 3066 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84577 | Pre-made Rat Hdac2 siRNA oligo Duplex | 84577 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15182 | Pre-made Mouse Hdac2/YAF1/Yy1bp siRNA oligo Duplex | 15182 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694662 | Pre-made Cynomolgus/Rhesus macaque HDAC2 siRNA oligo Duplex | 694662 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088165 | Pre-made Cat/Feline HDAC2 siRNA oligo Duplex | 101088165 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475035 | Pre-made Dog/Canine HDAC2 siRNA oligo Duplex | 475035 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407223 | Pre-made Bovines/Cattle HDAC2 siRNA oligo Duplex | 407223 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072578 | Pre-made Equine/Horse HDAC2 siRNA oligo Duplex | 100072578 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HDAC2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T51191-Ab | Human | Anti-Human HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T51191-Ab | Rat | Anti-Rat HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T51191-Ab | Mouse | Anti-Mouse HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T51191-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T51191-Ab | Cat/Feline | Anti-Cat/Feline HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T51191-Ab | Dog/Canine | Anti-Dog/Canine HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T51191-Ab | Bovines/Cattle | Anti-Bovines/Cattle HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T51191-Ab | Equine/Horse | Anti-Equine/Horse HDAC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HDAC2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T51191-Ag | Human | Human HDAC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T51191-Ag | Rat | Rat HDAC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T51191-Ag | Mouse | Mouse HDAC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T51191-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HDAC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T51191-Ag | Cat/Feline | Cat/Feline HDAC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T51191-Ag | Dog/Canine | Dog/Canine HDAC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T51191-Ag | Bovines/Cattle | Bovines/Cattle HDAC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T51191-Ag | Equine/Horse | Equine/Horse HDAC2 recombinant protein | Mammalian cell | Detail |
