Recombinant multi-species EIF2AK2/PKR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF2AK2/PKR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021]
The Alternative Names of target: EIF2AK2, PKR,Interferon-induced, double-stranded RNA-activated protein kinase,Eukaryotic translation initiation factor 2-alpha kinase 2 (eIF-2A protein kinase 2), Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase RNA-activated (PKR, Protein kinase R), Tyrosine-protein kinase EIF2AK2, p68 kinase,PKR,PRKR,DYT33,LEUDEN,EIF2AK1,PPP1R83

Target products collectionGo to EIF2AK2/PKR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T51102-Ab-1/ GM-Tg-hg-T51102-Ab-2 Human EIF2AK2/PKR protein Human
GM-Tg-rg-T51102-Ab-1/ GM-Tg-rg-T51102-Ab-2 Rat EIF2AK2/PKR protein Rat
GM-Tg-mg-T51102-Ab-1/ GM-Tg-mg-T51102-Ab-2 Mouse EIF2AK2/PKR protein Mouse
GM-Tg-cynog-T51102-Ab-1/ GM-Tg-cynog-T51102-Ab-2 Cynomolgus/Rhesus macaque EIF2AK2/PKR monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T51102-Ab-1/ GM-Tg-felg-T51102-Ab-2 Feline EIF2AK2/PKR protein Feline
GM-Tg-cang-T51102-Ab-1/ GM-Tg-cang-T51102-Ab-2 Canine EIF2AK2/PKR protein Canine
GM-Tg-bovg-T51102-Ab-1/ GM-Tg-bovg-T51102-Ab-2 Bovine EIF2AK2/PKR protein Bovine
GM-Tg-equg-T51102-Ab-1/ GM-Tg-equg-T51102-Ab-2 Equine EIF2AK2/PKR protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T51102-Ab-1/ GM-Tg-hg-T51102-Ab-2; GM-Tg-rg-T51102-Ab-1/ GM-Tg-rg-T51102-Ab-2;
GM-Tg-mg-T51102-Ab-1/ GM-Tg-mg-T51102-Ab-2; GM-Tg-cynog-T51102-Ab-1/ GM-Tg-cynog-T51102-Ab-2;
GM-Tg-felg-T51102-Ab-1/ GM-Tg-felg-T51102-Ab-2; GM-Tg-cang-T51102-Ab-1/ GM-Tg-cang-T51102-Ab-2;
GM-Tg-bovg-T51102-Ab-1/ GM-Tg-bovg-T51102-Ab-2; GM-Tg-equg-T51102-Ab-1/ GM-Tg-equg-T51102-Ab-2
Products Name EIF2AK2/PKR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EIF2AK2/PKR
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF2AK2/PKR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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