Recombinant multi-species PIM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PIM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
The Alternative Names of target: PIM,PIM1,Pim-1,Pim1,Serine/threonine-protein kinase pim-1,pim-1

Target products collectionGo to PIM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T50594-Ag-1/ GM-Tg-hg-T50594-Ag-2 Human PIM1 protein Human
GM-Tg-rg-T50594-Ag-1/ GM-Tg-rg-T50594-Ag-2 Rat PIM1 protein Rat
GM-Tg-mg-T50594-Ag-1/ GM-Tg-mg-T50594-Ag-2 Mouse PIM1 protein Mouse
GM-Tg-cynog-T50594-Ag-1/ GM-Tg-cynog-T50594-Ag-2 Cynomolgus/Rhesus macaque PIM1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T50594-Ag-1/ GM-Tg-felg-T50594-Ag-2 Feline PIM1 protein Feline
GM-Tg-cang-T50594-Ag-1/ GM-Tg-cang-T50594-Ag-2 Canine PIM1 protein Canine
GM-Tg-bovg-T50594-Ag-1/ GM-Tg-bovg-T50594-Ag-2 Bovine PIM1 protein Bovine
GM-Tg-equg-T50594-Ag-1/ GM-Tg-equg-T50594-Ag-2 Equine PIM1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T50594-Ag-1/ GM-Tg-hg-T50594-Ag-2; GM-Tg-rg-T50594-Ag-1/ GM-Tg-rg-T50594-Ag-2;
GM-Tg-mg-T50594-Ag-1/ GM-Tg-mg-T50594-Ag-2; GM-Tg-cynog-T50594-Ag-1/ GM-Tg-cynog-T50594-Ag-2;
GM-Tg-felg-T50594-Ag-1/ GM-Tg-felg-T50594-Ag-2; GM-Tg-cang-T50594-Ag-1/ GM-Tg-cang-T50594-Ag-2;
GM-Tg-bovg-T50594-Ag-1/ GM-Tg-bovg-T50594-Ag-2; GM-Tg-equg-T50594-Ag-1/ GM-Tg-equg-T50594-Ag-2
Products Name PIM1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PIM1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PIM1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.