Recombinant multi-species HPSE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HPSE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
The Alternative Names of target: Endo-glucoronidase,HPA,HPA1,HPR1,HPSE,HPSE1,HSE1,Hep,Heparanase,Heparanase-1 (Hpa1),Hpa,Hpr1,Hpse

Target products collectionGo to HPSE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T47623-Ag-1/ GM-Tg-hg-T47623-Ag-2 Human HPSE protein Human
GM-Tg-rg-T47623-Ag-1/ GM-Tg-rg-T47623-Ag-2 Rat HPSE protein Rat
GM-Tg-mg-T47623-Ag-1/ GM-Tg-mg-T47623-Ag-2 Mouse HPSE protein Mouse
GM-Tg-cynog-T47623-Ag-1/ GM-Tg-cynog-T47623-Ag-2 Cynomolgus/Rhesus macaque HPSE protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T47623-Ag-1/ GM-Tg-felg-T47623-Ag-2 Feline HPSE protein Feline
GM-Tg-cang-T47623-Ag-1/ GM-Tg-cang-T47623-Ag-2 Canine HPSE protein Canine
GM-Tg-bovg-T47623-Ag-1/ GM-Tg-bovg-T47623-Ag-2 Bovine HPSE protein Bovine
GM-Tg-equg-T47623-Ag-1/ GM-Tg-equg-T47623-Ag-2 Equine HPSE protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T47623-Ag-1/ GM-Tg-hg-T47623-Ag-2; GM-Tg-rg-T47623-Ag-1/ GM-Tg-rg-T47623-Ag-2;
GM-Tg-mg-T47623-Ag-1/ GM-Tg-mg-T47623-Ag-2; GM-Tg-cynog-T47623-Ag-1/ GM-Tg-cynog-T47623-Ag-2;
GM-Tg-felg-T47623-Ag-1/ GM-Tg-felg-T47623-Ag-2; GM-Tg-cang-T47623-Ag-1/ GM-Tg-cang-T47623-Ag-2;
GM-Tg-bovg-T47623-Ag-1/ GM-Tg-bovg-T47623-Ag-2; GM-Tg-equg-T47623-Ag-1/ GM-Tg-equg-T47623-Ag-2
Products Name HPSE protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HPSE
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HPSE protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.