Recombinant multi-species PKC Gamma/PRKCG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKC Gamma/PRKCG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
The Alternative Names of target: PKC,PKC Gamma,PKC-gamma,PKCC,PKCG,PKCI,PKCI(3),PKCgamma,PRKCG,Pkcc,Prkc,Prkcc,Prkcg,Protein kinase C gamma type,RATPKCI,SCA14

Target products collectionGo to PKC Gamma/PRKCG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T47107-Ag-1/ GM-Tg-hg-T47107-Ag-2 Human PKC Gamma/PRKCG protein Human
GM-Tg-rg-T47107-Ag-1/ GM-Tg-rg-T47107-Ag-2 Rat PKC Gamma/PRKCG protein Rat
GM-Tg-mg-T47107-Ag-1/ GM-Tg-mg-T47107-Ag-2 Mouse PKC Gamma/PRKCG protein Mouse
GM-Tg-cynog-T47107-Ag-1/ GM-Tg-cynog-T47107-Ag-2 Cynomolgus/Rhesus macaque PKC Gamma/PRKCG protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T47107-Ag-1/ GM-Tg-felg-T47107-Ag-2 Feline PKC Gamma/PRKCG protein Feline
GM-Tg-cang-T47107-Ag-1/ GM-Tg-cang-T47107-Ag-2 Canine PKC Gamma/PRKCG protein Canine
GM-Tg-bovg-T47107-Ag-1/ GM-Tg-bovg-T47107-Ag-2 Bovine PKC Gamma/PRKCG protein Bovine
GM-Tg-equg-T47107-Ag-1/ GM-Tg-equg-T47107-Ag-2 Equine PKC Gamma/PRKCG protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T47107-Ag-1/ GM-Tg-hg-T47107-Ag-2; GM-Tg-rg-T47107-Ag-1/ GM-Tg-rg-T47107-Ag-2;
GM-Tg-mg-T47107-Ag-1/ GM-Tg-mg-T47107-Ag-2; GM-Tg-cynog-T47107-Ag-1/ GM-Tg-cynog-T47107-Ag-2;
GM-Tg-felg-T47107-Ag-1/ GM-Tg-felg-T47107-Ag-2; GM-Tg-cang-T47107-Ag-1/ GM-Tg-cang-T47107-Ag-2;
GM-Tg-bovg-T47107-Ag-1/ GM-Tg-bovg-T47107-Ag-2; GM-Tg-equg-T47107-Ag-1/ GM-Tg-equg-T47107-Ag-2
Products Name PKC Gamma/PRKCG protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PKC Gamma/PRKCG
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKC Gamma/PRKCG protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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