Recombinant multi-species CDK9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CDK9,Cyclin-dependent kinase 9,C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit,TAK,C-2k,CTK1,CDC2L4,PITALRE

Target products collectionGo to CDK9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T44458-Ab-1/ GM-Tg-hg-T44458-Ab-2 Human CDK9 protein Human
GM-Tg-rg-T44458-Ab-1/ GM-Tg-rg-T44458-Ab-2 Rat CDK9 protein Rat
GM-Tg-mg-T44458-Ab-1/ GM-Tg-mg-T44458-Ab-2 Mouse CDK9 protein Mouse
GM-Tg-cynog-T44458-Ab-1/ GM-Tg-cynog-T44458-Ab-2 Cynomolgus/Rhesus macaque CDK9 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T44458-Ab-1/ GM-Tg-felg-T44458-Ab-2 Feline CDK9 protein Feline
GM-Tg-cang-T44458-Ab-1/ GM-Tg-cang-T44458-Ab-2 Canine CDK9 protein Canine
GM-Tg-bovg-T44458-Ab-1/ GM-Tg-bovg-T44458-Ab-2 Bovine CDK9 protein Bovine
GM-Tg-equg-T44458-Ab-1/ GM-Tg-equg-T44458-Ab-2 Equine CDK9 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T44458-Ab-1/ GM-Tg-hg-T44458-Ab-2; GM-Tg-rg-T44458-Ab-1/ GM-Tg-rg-T44458-Ab-2;
GM-Tg-mg-T44458-Ab-1/ GM-Tg-mg-T44458-Ab-2; GM-Tg-cynog-T44458-Ab-1/ GM-Tg-cynog-T44458-Ab-2;
GM-Tg-felg-T44458-Ab-1/ GM-Tg-felg-T44458-Ab-2; GM-Tg-cang-T44458-Ab-1/ GM-Tg-cang-T44458-Ab-2;
GM-Tg-bovg-T44458-Ab-1/ GM-Tg-bovg-T44458-Ab-2; GM-Tg-equg-T44458-Ab-1/ GM-Tg-equg-T44458-Ab-2
Products Name CDK9 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CDK9
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK9 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.