Explore CDK9 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
Target ID |
GM-T44458
|
Target Name |
CDK9
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1025
|
Gene ID |
100070437 (Equus caballus), 100855805 (Canis lupus familiaris), 101097767 (Felis catus), 1025 (Homo sapiens) 107951 (Mus musculus), 362110 (Rattus norvegicus), 520580 (Bos taurus), 699840 (Macaca mulatta)
|
Target Alternative Names |
CDK9,Cdk9,TAK,C-2k,CTK1,CDC2L4,PITALRE
|
Uniprot Accession |
P50750,Q99J95,Q641Z4,Q5EAB2
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
cancer
|
Disease from KEGG |
|
Gene Ensembl |
ENSG00000136807, ENSMUSG00000009555, ENSMMUG00000054306
|
Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CDK9 cDNA Clones/ORF Plasmid
CDK9 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo1025 | Pre-made Human CDK9/TAK/C-2k siRNA oligo Duplex | 1025 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo362110 | Pre-made Rat Cdk9 siRNA oligo Duplex | 362110 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo107951 | Pre-made Mouse Cdk9/PITALRE siRNA oligo Duplex | 107951 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo699840 | Pre-made Cynomolgus/Rhesus macaque CDK9 siRNA oligo Duplex | 699840 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101097767 | Pre-made Cat/Feline CDK9 siRNA oligo Duplex | 101097767 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo100855805 | Pre-made Dog/Canine CDK9 siRNA oligo Duplex | 100855805 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo520580 | Pre-made Bovines/Cattle CDK9 siRNA oligo Duplex | 520580 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100070437 | Pre-made Equine/Horse CDK9 siRNA oligo Duplex | 100070437 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CDK9 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T44458-Ab | Human | Anti-Human CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-T44458-Ab | Rat | Anti-Rat CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-T44458-Ab | Mouse | Anti-Mouse CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-T44458-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-T44458-Ab | Cat/Feline | Anti-Cat/Feline CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-T44458-Ab | Dog/Canine | Anti-Dog/Canine CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-T44458-Ab | Bovines/Cattle | Anti-Bovines/Cattle CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-T44458-Ab | Equine/Horse | Anti-Equine/Horse CDK9 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CDK9 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T44458-Ag | Human | Human CDK9 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T44458-Ag | Rat | Rat CDK9 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T44458-Ag | Mouse | Mouse CDK9 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T44458-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CDK9 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T44458-Ag | Cat/Feline | Cat/Feline CDK9 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T44458-Ag | Dog/Canine | Dog/Canine CDK9 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T44458-Ag | Bovines/Cattle | Bovines/Cattle CDK9 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T44458-Ag | Equine/Horse | Equine/Horse CDK9 recombinant protein | Mammalian cell | Detail |