Recombinant multi-species RORA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RORA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
The Alternative Names of target: RORA,Nuclear receptor ROR-alpha,Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha,ROR1,ROR2,ROR3,RZRA,NR1F1,RORa1,IDDECA,RORalpha,RZR-ALPHA

Target products collectionGo to RORA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T43206-Ab-1/ GM-Tg-hg-T43206-Ab-2 Human RORA protein Human
GM-Tg-rg-T43206-Ab-1/ GM-Tg-rg-T43206-Ab-2 Rat RORA protein Rat
GM-Tg-mg-T43206-Ab-1/ GM-Tg-mg-T43206-Ab-2 Mouse RORA protein Mouse
GM-Tg-cynog-T43206-Ab-1/ GM-Tg-cynog-T43206-Ab-2 Cynomolgus/Rhesus macaque RORA monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T43206-Ab-1/ GM-Tg-felg-T43206-Ab-2 Feline RORA protein Feline
GM-Tg-cang-T43206-Ab-1/ GM-Tg-cang-T43206-Ab-2 Canine RORA protein Canine
GM-Tg-bovg-T43206-Ab-1/ GM-Tg-bovg-T43206-Ab-2 Bovine RORA protein Bovine
GM-Tg-equg-T43206-Ab-1/ GM-Tg-equg-T43206-Ab-2 Equine RORA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T43206-Ab-1/ GM-Tg-hg-T43206-Ab-2; GM-Tg-rg-T43206-Ab-1/ GM-Tg-rg-T43206-Ab-2;
GM-Tg-mg-T43206-Ab-1/ GM-Tg-mg-T43206-Ab-2; GM-Tg-cynog-T43206-Ab-1/ GM-Tg-cynog-T43206-Ab-2;
GM-Tg-felg-T43206-Ab-1/ GM-Tg-felg-T43206-Ab-2; GM-Tg-cang-T43206-Ab-1/ GM-Tg-cang-T43206-Ab-2;
GM-Tg-bovg-T43206-Ab-1/ GM-Tg-bovg-T43206-Ab-2; GM-Tg-equg-T43206-Ab-1/ GM-Tg-equg-T43206-Ab-2
Products Name RORA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RORA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RORA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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