Explore RORA gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Target ID |
GM-T43206
|
Target Name |
RORA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6095
|
Gene ID |
100147460 (Equus caballus), 101099721 (Felis catus), 119866906 (Canis lupus familiaris), 19883 (Mus musculus) 300807 (Rattus norvegicus), 535597 (Bos taurus), 6095 (Homo sapiens), 704014 (Macaca mulatta)
|
Target Alternative Names |
RORA,Rora,sg,ROR1,ROR2,ROR3,Nr1f1,nmf267,tmgc26,staggerer,9530021D13Rik,RZRA,NR1F1,RORa1,IDDECA,RORalpha,RZR-ALPHA
|
Uniprot Accession |
P51448,P35398
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
Th17 cell differentiation, Inflammatory bowel disease
|
Gene Ensembl |
ENSECAG00000016384, ENSCAFG00845017841, ENSMUSG00000032238, ENSBTAG00000015904, ENSG00000069667, ENSMMUG00000018192
|
Target Classification |
|
Pre-made viral vector of RORA cDNA Clones/ORF Plasmid
RORA siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo6095 | Pre-made Human RORA/ROR1/ROR2 siRNA oligo Duplex | 6095 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo300807 | Pre-made Rat Rora siRNA oligo Duplex | 300807 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo19883 | Pre-made Mouse Rora/sg/ROR1 siRNA oligo Duplex | 19883 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo704014 | Pre-made Cynomolgus/Rhesus macaque RORA siRNA oligo Duplex | 704014 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101099721 | Pre-made Cat/Feline RORA siRNA oligo Duplex | 101099721 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo119866906 | Pre-made Dog/Canine RORA siRNA oligo Duplex | 119866906 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo535597 | Pre-made Bovines/Cattle RORA siRNA oligo Duplex | 535597 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100147460 | Pre-made Equine/Horse RORA siRNA oligo Duplex | 100147460 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RORA antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T43206-Ab | Human | Anti-Human RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-T43206-Ab | Rat | Anti-Rat RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-T43206-Ab | Mouse | Anti-Mouse RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-T43206-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-T43206-Ab | Cat/Feline | Anti-Cat/Feline RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-T43206-Ab | Dog/Canine | Anti-Dog/Canine RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-T43206-Ab | Bovines/Cattle | Anti-Bovines/Cattle RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-T43206-Ab | Equine/Horse | Anti-Equine/Horse RORA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RORA recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T43206-Ag | Human | Human RORA recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T43206-Ag | Rat | Rat RORA recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T43206-Ag | Mouse | Mouse RORA recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T43206-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RORA recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T43206-Ag | Cat/Feline | Cat/Feline RORA recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T43206-Ag | Dog/Canine | Dog/Canine RORA recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T43206-Ag | Bovines/Cattle | Bovines/Cattle RORA recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T43206-Ag | Equine/Horse | Equine/Horse RORA recombinant protein | Mammalian cell | Detail |