Recombinant multi-species FECH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FECH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]
The Alternative Names of target: EPP,EPP1,FCE,FECH,Fcl,Fech,Ferrochelatase,Heme synthase,Protoheme ferro-lyase,fch,mitochondrial

Target products collectionGo to FECH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T42822-Ag-1/ GM-Tg-hg-T42822-Ag-2 Human FECH protein Human
GM-Tg-rg-T42822-Ag-1/ GM-Tg-rg-T42822-Ag-2 Rat FECH protein Rat
GM-Tg-mg-T42822-Ag-1/ GM-Tg-mg-T42822-Ag-2 Mouse FECH protein Mouse
GM-Tg-cynog-T42822-Ag-1/ GM-Tg-cynog-T42822-Ag-2 Cynomolgus/Rhesus macaque FECH protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T42822-Ag-1/ GM-Tg-felg-T42822-Ag-2 Feline FECH protein Feline
GM-Tg-cang-T42822-Ag-1/ GM-Tg-cang-T42822-Ag-2 Canine FECH protein Canine
GM-Tg-bovg-T42822-Ag-1/ GM-Tg-bovg-T42822-Ag-2 Bovine FECH protein Bovine
GM-Tg-equg-T42822-Ag-1/ GM-Tg-equg-T42822-Ag-2 Equine FECH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T42822-Ag-1/ GM-Tg-hg-T42822-Ag-2; GM-Tg-rg-T42822-Ag-1/ GM-Tg-rg-T42822-Ag-2;
GM-Tg-mg-T42822-Ag-1/ GM-Tg-mg-T42822-Ag-2; GM-Tg-cynog-T42822-Ag-1/ GM-Tg-cynog-T42822-Ag-2;
GM-Tg-felg-T42822-Ag-1/ GM-Tg-felg-T42822-Ag-2; GM-Tg-cang-T42822-Ag-1/ GM-Tg-cang-T42822-Ag-2;
GM-Tg-bovg-T42822-Ag-1/ GM-Tg-bovg-T42822-Ag-2; GM-Tg-equg-T42822-Ag-1/ GM-Tg-equg-T42822-Ag-2
Products Name FECH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FECH
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FECH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.