Explore FECH gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]
| Target ID |
GM-T42822
|
| Target Name |
FECH
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2235
|
| Gene ID |
100054014 (Equus caballus), 101087879 (Felis catus), 14151 (Mus musculus), 2235 (Homo sapiens)
281158 (Bos taurus), 361338 (Rattus norvegicus), 610360 (Canis lupus familiaris), 695759 (Macaca mulatta)
|
| Target Alternative Names |
EPP,EPP1,FCE,FECH,Fcl,Fech,Ferrochelatase,Heme synthase,Protoheme ferro-lyase,fch,mitochondrial
|
| Uniprot Accession |
P22315,P22830,P22600
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Tumors
|
| Disease from KEGG |
Metabolic pathways, Porphyrin metabolism
|
| Gene Ensembl |
ENSECAG00000012137, ENSMUSG00000024588, ENSG00000066926, ENSBTAG00000006393, ENSCAFG00845001850, ENSMMUG00000022568
|
Pre-made viral vector of FECH cDNA Clones/ORF Plasmid
FECH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2235 | Pre-made Human FECH/EPP/FCE siRNA oligo Duplex | 2235 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361338 | Pre-made Rat Fech siRNA oligo Duplex | 361338 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14151 | Pre-made Mouse Fech/Fcl/fch siRNA oligo Duplex | 14151 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695759 | Pre-made Cynomolgus/Rhesus macaque FECH siRNA oligo Duplex | 695759 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087879 | Pre-made Cat/Feline FECH siRNA oligo Duplex | 101087879 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610360 | Pre-made Dog/Canine FECH siRNA oligo Duplex | 610360 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281158 | Pre-made Bovines/Cattle FECH siRNA oligo Duplex | 281158 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054014 | Pre-made Equine/Horse FECH siRNA oligo Duplex | 100054014 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FECH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T42822-Ab | Human | Anti-Human FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T42822-Ab | Rat | Anti-Rat FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T42822-Ab | Mouse | Anti-Mouse FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T42822-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T42822-Ab | Cat/Feline | Anti-Cat/Feline FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T42822-Ab | Dog/Canine | Anti-Dog/Canine FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T42822-Ab | Bovines/Cattle | Anti-Bovines/Cattle FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T42822-Ab | Equine/Horse | Anti-Equine/Horse FECH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
FECH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T42822-Ag | Human | Human FECH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T42822-Ag | Rat | Rat FECH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T42822-Ag | Mouse | Mouse FECH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T42822-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FECH recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T42822-Ag | Cat/Feline | Cat/Feline FECH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T42822-Ag | Dog/Canine | Dog/Canine FECH recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T42822-Ag | Bovines/Cattle | Bovines/Cattle FECH recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T42822-Ag | Equine/Horse | Equine/Horse FECH recombinant protein | Mammalian cell | Detail |
