Recombinant multi-species NME1/NM23-H1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NME1/NM23-H1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AWD,GAAD,Granzyme A-activated DNase (GAAD),Metastasis inhibition factor nm23,NB,NBS,NDK A,NDKA,NDP kinase A,NDPK-A,NDPKA,NM23,NM23-H1,NME1,Nucleoside diphosphate kinase A,Tumor metastatic process-associated protein

Target products collectionGo to NME1/NM23-H1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T42533-Ag-1/ GM-Tg-hg-T42533-Ag-2 Human NME1/NM23-H1 protein Human
GM-Tg-rg-T42533-Ag-1/ GM-Tg-rg-T42533-Ag-2 Rat NME1/NM23-H1 protein Rat
GM-Tg-mg-T42533-Ag-1/ GM-Tg-mg-T42533-Ag-2 Mouse NME1/NM23-H1 protein Mouse
GM-Tg-cynog-T42533-Ag-1/ GM-Tg-cynog-T42533-Ag-2 Cynomolgus/Rhesus macaque NME1/NM23-H1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T42533-Ag-1/ GM-Tg-felg-T42533-Ag-2 Feline NME1/NM23-H1 protein Feline
GM-Tg-cang-T42533-Ag-1/ GM-Tg-cang-T42533-Ag-2 Canine NME1/NM23-H1 protein Canine
GM-Tg-bovg-T42533-Ag-1/ GM-Tg-bovg-T42533-Ag-2 Bovine NME1/NM23-H1 protein Bovine
GM-Tg-equg-T42533-Ag-1/ GM-Tg-equg-T42533-Ag-2 Equine NME1/NM23-H1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T42533-Ag-1/ GM-Tg-hg-T42533-Ag-2; GM-Tg-rg-T42533-Ag-1/ GM-Tg-rg-T42533-Ag-2;
GM-Tg-mg-T42533-Ag-1/ GM-Tg-mg-T42533-Ag-2; GM-Tg-cynog-T42533-Ag-1/ GM-Tg-cynog-T42533-Ag-2;
GM-Tg-felg-T42533-Ag-1/ GM-Tg-felg-T42533-Ag-2; GM-Tg-cang-T42533-Ag-1/ GM-Tg-cang-T42533-Ag-2;
GM-Tg-bovg-T42533-Ag-1/ GM-Tg-bovg-T42533-Ag-2; GM-Tg-equg-T42533-Ag-1/ GM-Tg-equg-T42533-Ag-2
Products Name NME1/NM23-H1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NME1/NM23-H1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NME1/NM23-H1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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