Recombinant multi-species EPX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EPX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]
The Alternative Names of target: EPO,EPP,EPX,EPX-PEN,EPXD,Eosinophil peroxidase,Epx

Target products collectionGo to EPX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T42319-Ag-1/ GM-Tg-hg-T42319-Ag-2 Human EPX protein Human
GM-Tg-rg-T42319-Ag-1/ GM-Tg-rg-T42319-Ag-2 Rat EPX protein Rat
GM-Tg-mg-T42319-Ag-1/ GM-Tg-mg-T42319-Ag-2 Mouse EPX protein Mouse
GM-Tg-cynog-T42319-Ag-1/ GM-Tg-cynog-T42319-Ag-2 Cynomolgus/Rhesus macaque EPX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T42319-Ag-1/ GM-Tg-felg-T42319-Ag-2 Feline EPX protein Feline
GM-Tg-cang-T42319-Ag-1/ GM-Tg-cang-T42319-Ag-2 Canine EPX protein Canine
GM-Tg-bovg-T42319-Ag-1/ GM-Tg-bovg-T42319-Ag-2 Bovine EPX protein Bovine
GM-Tg-equg-T42319-Ag-1/ GM-Tg-equg-T42319-Ag-2 Equine EPX protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T42319-Ag-1/ GM-Tg-hg-T42319-Ag-2; GM-Tg-rg-T42319-Ag-1/ GM-Tg-rg-T42319-Ag-2;
GM-Tg-mg-T42319-Ag-1/ GM-Tg-mg-T42319-Ag-2; GM-Tg-cynog-T42319-Ag-1/ GM-Tg-cynog-T42319-Ag-2;
GM-Tg-felg-T42319-Ag-1/ GM-Tg-felg-T42319-Ag-2; GM-Tg-cang-T42319-Ag-1/ GM-Tg-cang-T42319-Ag-2;
GM-Tg-bovg-T42319-Ag-1/ GM-Tg-bovg-T42319-Ag-2; GM-Tg-equg-T42319-Ag-1/ GM-Tg-equg-T42319-Ag-2
Products Name EPX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EPX
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EPX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.