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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]
| Target ID |
GM-T42319
|
| Target Name |
EPX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8288
|
| Gene ID |
100070907 (Equus caballus), 13861 (Mus musculus), 303414 (Rattus norvegicus), 491109 (Canis lupus familiaris)
709655 (Macaca mulatta), 8288 (Homo sapiens)
|
| Target Alternative Names |
EPO,EPP,EPX,EPX-PEN,EPXD,Eosinophil peroxidase,Epx
|
| Uniprot Accession |
P49290,P11678
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Asthma
|
| Gene Ensembl |
ENSECAG00000017317, ENSMUSG00000052234, ENSCAFG00845017713, ENSMMUG00000011973, ENSG00000121053
|
EPX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8288 | Pre-made Human EPX/EPO/EPP siRNA oligo Duplex | 8288 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo303414 | Pre-made Rat Epx siRNA oligo Duplex | 303414 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13861 | Pre-made Mouse Epx/EPO siRNA oligo Duplex | 13861 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709655 | Pre-made Cynomolgus/Rhesus macaque EPX siRNA oligo Duplex | 709655 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491109 | Pre-made Dog/Canine EPX siRNA oligo Duplex | 491109 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070907 | Pre-made Equine/Horse EPX siRNA oligo Duplex | 100070907 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EPX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T42319-Ab | Human | Anti-Human EPX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T42319-Ab | Rat | Anti-Rat EPX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T42319-Ab | Mouse | Anti-Mouse EPX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T42319-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EPX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T42319-Ab | Dog/Canine | Anti-Dog/Canine EPX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T42319-Ab | Equine/Horse | Anti-Equine/Horse EPX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EPX recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T42319-Ag | Human | Human EPX recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T42319-Ag | Rat | Rat EPX recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T42319-Ag | Mouse | Mouse EPX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T42319-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EPX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T42319-Ag | Dog/Canine | Dog/Canine EPX recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T42319-Ag | Equine/Horse | Equine/Horse EPX recombinant protein | Mammalian cell | Detail |
