Recombinant multi-species XDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine XDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
The Alternative Names of target: XDH,Xanthine dehydrogenase/oxidase,XO,XOR,XAN1
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T40954-Ab-1/ GM-Tg-hg-T40954-Ab-2 | Human XDH protein | Human |
GM-Tg-rg-T40954-Ab-1/ GM-Tg-rg-T40954-Ab-2 | Rat XDH protein | Rat |
GM-Tg-mg-T40954-Ab-1/ GM-Tg-mg-T40954-Ab-2 | Mouse XDH protein | Mouse |
GM-Tg-cynog-T40954-Ab-1/ GM-Tg-cynog-T40954-Ab-2 | Cynomolgus/Rhesus macaque XDH monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T40954-Ab-1/ GM-Tg-felg-T40954-Ab-2 | Feline XDH protein | Feline |
GM-Tg-cang-T40954-Ab-1/ GM-Tg-cang-T40954-Ab-2 | Canine XDH protein | Canine |
GM-Tg-bovg-T40954-Ab-1/ GM-Tg-bovg-T40954-Ab-2 | Bovine XDH protein | Bovine |
GM-Tg-equg-T40954-Ab-1/ GM-Tg-equg-T40954-Ab-2 | Equine XDH protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T40954-Ab-1/ GM-Tg-hg-T40954-Ab-2;
GM-Tg-rg-T40954-Ab-1/ GM-Tg-rg-T40954-Ab-2;
GM-Tg-mg-T40954-Ab-1/ GM-Tg-mg-T40954-Ab-2; GM-Tg-cynog-T40954-Ab-1/ GM-Tg-cynog-T40954-Ab-2; GM-Tg-felg-T40954-Ab-1/ GM-Tg-felg-T40954-Ab-2; GM-Tg-cang-T40954-Ab-1/ GM-Tg-cang-T40954-Ab-2; GM-Tg-bovg-T40954-Ab-1/ GM-Tg-bovg-T40954-Ab-2; GM-Tg-equg-T40954-Ab-1/ GM-Tg-equg-T40954-Ab-2 |
Products Name | XDH protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | XDH |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine XDH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.