Recombinant multi-species XDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine XDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
The Alternative Names of target: XDH,Xanthine dehydrogenase/oxidase,XO,XOR,XAN1

Target products collectionGo to XDH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T40954-Ab-1/ GM-Tg-hg-T40954-Ab-2 Human XDH protein Human
GM-Tg-rg-T40954-Ab-1/ GM-Tg-rg-T40954-Ab-2 Rat XDH protein Rat
GM-Tg-mg-T40954-Ab-1/ GM-Tg-mg-T40954-Ab-2 Mouse XDH protein Mouse
GM-Tg-cynog-T40954-Ab-1/ GM-Tg-cynog-T40954-Ab-2 Cynomolgus/Rhesus macaque XDH monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T40954-Ab-1/ GM-Tg-felg-T40954-Ab-2 Feline XDH protein Feline
GM-Tg-cang-T40954-Ab-1/ GM-Tg-cang-T40954-Ab-2 Canine XDH protein Canine
GM-Tg-bovg-T40954-Ab-1/ GM-Tg-bovg-T40954-Ab-2 Bovine XDH protein Bovine
GM-Tg-equg-T40954-Ab-1/ GM-Tg-equg-T40954-Ab-2 Equine XDH protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T40954-Ab-1/ GM-Tg-hg-T40954-Ab-2; GM-Tg-rg-T40954-Ab-1/ GM-Tg-rg-T40954-Ab-2;
GM-Tg-mg-T40954-Ab-1/ GM-Tg-mg-T40954-Ab-2; GM-Tg-cynog-T40954-Ab-1/ GM-Tg-cynog-T40954-Ab-2;
GM-Tg-felg-T40954-Ab-1/ GM-Tg-felg-T40954-Ab-2; GM-Tg-cang-T40954-Ab-1/ GM-Tg-cang-T40954-Ab-2;
GM-Tg-bovg-T40954-Ab-1/ GM-Tg-bovg-T40954-Ab-2; GM-Tg-equg-T40954-Ab-1/ GM-Tg-equg-T40954-Ab-2
Products Name XDH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name XDH
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine XDH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.