Explore XDH gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
| Target ID |
GM-T40954
|
| Target Name |
XDH
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7498
|
| Gene ID |
100054601 (Equus caballus), 22436 (Mus musculus), 280960 (Bos taurus), 483028 (Canis lupus familiaris)
497811 (Rattus norvegicus), 708046 (Macaca mulatta), 7498 (Homo sapiens)
|
| Target Alternative Names |
XDH,Xdh,XO,Xor,Xox1,Xox-1,XOR,XAN1
|
| Uniprot Accession |
Q00519,P80457,P22985,P47989
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000039673, ENSMUSG00000024066, ENSBTAG00000012519, ENSCAFG00845012424, ENSMMUG00000000561, ENSG00000158125
|
| Target Classification |
|
Pre-made viral vector of XDH cDNA Clones/ORF Plasmid
XDH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7498 | Pre-made Human XDH/XO/XOR siRNA oligo Duplex | 7498 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497811 | Pre-made Rat Xdh/XOR siRNA oligo Duplex | 497811 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22436 | Pre-made Mouse Xdh/XO/Xor siRNA oligo Duplex | 22436 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708046 | Pre-made Cynomolgus/Rhesus macaque XDH siRNA oligo Duplex | 708046 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483028 | Pre-made Dog/Canine XDH siRNA oligo Duplex | 483028 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280960 | Pre-made Bovines/Cattle XDH/XOR siRNA oligo Duplex | 280960 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054601 | Pre-made Equine/Horse XDH siRNA oligo Duplex | 100054601 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
XDH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T40954-Ab | Human | Anti-Human XDH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T40954-Ab | Rat | Anti-Rat XDH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T40954-Ab | Mouse | Anti-Mouse XDH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T40954-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque XDH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T40954-Ab | Dog/Canine | Anti-Dog/Canine XDH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T40954-Ab | Bovines/Cattle | Anti-Bovines/Cattle XDH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T40954-Ab | Equine/Horse | Anti-Equine/Horse XDH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
XDH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T40954-Ag | Human | Human XDH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T40954-Ag | Rat | Rat XDH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T40954-Ag | Mouse | Mouse XDH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T40954-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque XDH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T40954-Ag | Dog/Canine | Dog/Canine XDH recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T40954-Ag | Bovines/Cattle | Bovines/Cattle XDH recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T40954-Ag | Equine/Horse | Equine/Horse XDH recombinant protein | Mammalian cell | Detail |
