Recombinant multi-species MTAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MTAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2021]
The Alternative Names of target: 1300019I21Rik,5'-methylthioadenosine phosphorylase (MTA phosphorylase,BDMF,Cc1-6,DMSFH,DMSMFH,HEL-249,LGMBF,MSAP,MTAP,MTAPase,MTAPase),Mtap,S-methyl-5'-thioadenosine phosphorylase,c86fus

Target products collectionGo to MTAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T40787-Ag-1/ GM-Tg-hg-T40787-Ag-2 Human MTAP protein Human
GM-Tg-rg-T40787-Ag-1/ GM-Tg-rg-T40787-Ag-2 Rat MTAP protein Rat
GM-Tg-mg-T40787-Ag-1/ GM-Tg-mg-T40787-Ag-2 Mouse MTAP protein Mouse
GM-Tg-cynog-T40787-Ag-1/ GM-Tg-cynog-T40787-Ag-2 Cynomolgus/Rhesus macaque MTAP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T40787-Ag-1/ GM-Tg-felg-T40787-Ag-2 Feline MTAP protein Feline
GM-Tg-cang-T40787-Ag-1/ GM-Tg-cang-T40787-Ag-2 Canine MTAP protein Canine
GM-Tg-bovg-T40787-Ag-1/ GM-Tg-bovg-T40787-Ag-2 Bovine MTAP protein Bovine
GM-Tg-equg-T40787-Ag-1/ GM-Tg-equg-T40787-Ag-2 Equine MTAP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T40787-Ag-1/ GM-Tg-hg-T40787-Ag-2; GM-Tg-rg-T40787-Ag-1/ GM-Tg-rg-T40787-Ag-2;
GM-Tg-mg-T40787-Ag-1/ GM-Tg-mg-T40787-Ag-2; GM-Tg-cynog-T40787-Ag-1/ GM-Tg-cynog-T40787-Ag-2;
GM-Tg-felg-T40787-Ag-1/ GM-Tg-felg-T40787-Ag-2; GM-Tg-cang-T40787-Ag-1/ GM-Tg-cang-T40787-Ag-2;
GM-Tg-bovg-T40787-Ag-1/ GM-Tg-bovg-T40787-Ag-2; GM-Tg-equg-T40787-Ag-1/ GM-Tg-equg-T40787-Ag-2
Products Name MTAP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MTAP
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MTAP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.