Explore MTAP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2021]
| Target ID |
GM-T40787
|
| Target Name |
MTAP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4507
|
| Gene ID |
101088961 (Felis catus), 298227 (Rattus norvegicus), 4507 (Homo sapiens), 474729 (Canis lupus familiaris) 66902 (Mus musculus), 709020 (Macaca mulatta), 782907 (Bos taurus)
|
| Target Alternative Names |
1300019I21Rik,5'-methylthioadenosine phosphorylase (MTA phosphorylase,BDMF,Cc1-6,DMSFH,DMSMFH,HEL-249,LGMBF,MSAP,MTAP,MTAPase,MTAPase),Mtap,S-methyl-5'-thioadenosine phosphorylase,c86fus
|
| Uniprot Accession |
Q13126,Q9CQ65,F6RQL9
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSG00000099810, ENSCAFG00845016288, ENSMUSG00000062937, ENSMMUG00000001137, ENSBTAG00000025929
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of MTAP cDNA Clones/ORF Plasmid
MTAP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4507 | Pre-made Human MTAP/BDMF/MSAP siRNA oligo Duplex | 4507 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298227 | Pre-made Rat Mtap/Cc1-6 siRNA oligo Duplex | 298227 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo66902 | Pre-made Mouse Mtap/MSAP/1300019I21Rik siRNA oligo Duplex | 66902 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709020 | Pre-made Cynomolgus/Rhesus macaque MTAP/MTAPase siRNA oligo Duplex | 709020 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088961 | Pre-made Cat/Feline MTAP siRNA oligo Duplex | 101088961 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474729 | Pre-made Dog/Canine MTAP siRNA oligo Duplex | 474729 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo782907 | Pre-made Bovines/Cattle MTAP siRNA oligo Duplex | 782907 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
MTAP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T40787-Ab | Human | Anti-Human MTAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T40787-Ab | Rat | Anti-Rat MTAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T40787-Ab | Mouse | Anti-Mouse MTAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T40787-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MTAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T40787-Ab | Cat/Feline | Anti-Cat/Feline MTAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T40787-Ab | Dog/Canine | Anti-Dog/Canine MTAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T40787-Ab | Bovines/Cattle | Anti-Bovines/Cattle MTAP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MTAP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T40787-Ag | Human | Human MTAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T40787-Ag | Rat | Rat MTAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T40787-Ag | Mouse | Mouse MTAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T40787-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MTAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T40787-Ag | Cat/Feline | Cat/Feline MTAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T40787-Ag | Dog/Canine | Dog/Canine MTAP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T40787-Ag | Bovines/Cattle | Bovines/Cattle MTAP recombinant protein | Mammalian cell | Detail |