Recombinant multi-species PLK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]
The Alternative Names of target: PLK,PLK1,Plk,Plk1,Polo-like kinase 1 (PLK-1),STPK13,Serine/threonine-protein kinase 13 (STPK13),Serine/threonine-protein kinase PLK1

Target products collectionGo to PLK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T40694-Ag-1/ GM-Tg-hg-T40694-Ag-2 Human PLK1 protein Human
GM-Tg-rg-T40694-Ag-1/ GM-Tg-rg-T40694-Ag-2 Rat PLK1 protein Rat
GM-Tg-mg-T40694-Ag-1/ GM-Tg-mg-T40694-Ag-2 Mouse PLK1 protein Mouse
GM-Tg-cynog-T40694-Ag-1/ GM-Tg-cynog-T40694-Ag-2 Cynomolgus/Rhesus macaque PLK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T40694-Ag-1/ GM-Tg-felg-T40694-Ag-2 Feline PLK1 protein Feline
GM-Tg-cang-T40694-Ag-1/ GM-Tg-cang-T40694-Ag-2 Canine PLK1 protein Canine
GM-Tg-bovg-T40694-Ag-1/ GM-Tg-bovg-T40694-Ag-2 Bovine PLK1 protein Bovine
GM-Tg-equg-T40694-Ag-1/ GM-Tg-equg-T40694-Ag-2 Equine PLK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T40694-Ag-1/ GM-Tg-hg-T40694-Ag-2; GM-Tg-rg-T40694-Ag-1/ GM-Tg-rg-T40694-Ag-2;
GM-Tg-mg-T40694-Ag-1/ GM-Tg-mg-T40694-Ag-2; GM-Tg-cynog-T40694-Ag-1/ GM-Tg-cynog-T40694-Ag-2;
GM-Tg-felg-T40694-Ag-1/ GM-Tg-felg-T40694-Ag-2; GM-Tg-cang-T40694-Ag-1/ GM-Tg-cang-T40694-Ag-2;
GM-Tg-bovg-T40694-Ag-1/ GM-Tg-bovg-T40694-Ag-2; GM-Tg-equg-T40694-Ag-1/ GM-Tg-equg-T40694-Ag-2
Products Name PLK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PLK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.