Recombinant multi-species BRD4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRD4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: BRD4,Brd4,Brd5,Bromodomain-containing protein 4,CAP,CDLS6,FSHRG4,HUNK1,HUNKI,MCAP,Protein HUNK1,WI-11513

Target products collectionGo to BRD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T40556-Ag-1/ GM-Tg-hg-T40556-Ag-2 Human BRD4 protein Human
GM-Tg-rg-T40556-Ag-1/ GM-Tg-rg-T40556-Ag-2 Rat BRD4 protein Rat
GM-Tg-mg-T40556-Ag-1/ GM-Tg-mg-T40556-Ag-2 Mouse BRD4 protein Mouse
GM-Tg-cynog-T40556-Ag-1/ GM-Tg-cynog-T40556-Ag-2 Cynomolgus/Rhesus macaque BRD4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T40556-Ag-1/ GM-Tg-felg-T40556-Ag-2 Feline BRD4 protein Feline
GM-Tg-cang-T40556-Ag-1/ GM-Tg-cang-T40556-Ag-2 Canine BRD4 protein Canine
GM-Tg-bovg-T40556-Ag-1/ GM-Tg-bovg-T40556-Ag-2 Bovine BRD4 protein Bovine
GM-Tg-equg-T40556-Ag-1/ GM-Tg-equg-T40556-Ag-2 Equine BRD4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T40556-Ag-1/ GM-Tg-hg-T40556-Ag-2; GM-Tg-rg-T40556-Ag-1/ GM-Tg-rg-T40556-Ag-2;
GM-Tg-mg-T40556-Ag-1/ GM-Tg-mg-T40556-Ag-2; GM-Tg-cynog-T40556-Ag-1/ GM-Tg-cynog-T40556-Ag-2;
GM-Tg-felg-T40556-Ag-1/ GM-Tg-felg-T40556-Ag-2; GM-Tg-cang-T40556-Ag-1/ GM-Tg-cang-T40556-Ag-2;
GM-Tg-bovg-T40556-Ag-1/ GM-Tg-bovg-T40556-Ag-2; GM-Tg-equg-T40556-Ag-1/ GM-Tg-equg-T40556-Ag-2
Products Name BRD4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BRD4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRD4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.