Explore BRD4 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T40556
|
| Target Name |
BRD4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23476
|
| Gene ID |
100062072 (Equus caballus), 101100035 (Felis catus), 23476 (Homo sapiens), 362844 (Rattus norvegicus)
484869 (Canis lupus familiaris), 57261 (Mus musculus), 614048 (Bos taurus), 718195 (Macaca mulatta)
|
| Target Alternative Names |
BRD4,Brd4,Brd5,Bromodomain-containing protein 4,CAP,CDLS6,FSHRG4,HUNK1,HUNKI,MCAP,Protein HUNK1,WI-11513
|
| Uniprot Accession |
O60885,Q9ESU6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000030438, ENSG00000141867, ENSCAFG00845018129, ENSMUSG00000024002, ENSBTAG00000002495, ENSMMUG00000021382
|
| Target Classification |
Epigenetic, Kinase, Pathway, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of BRD4 cDNA Clones/ORF Plasmid
BRD4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23476 | Pre-made Human BRD4/CAP/MCAP siRNA oligo Duplex | 23476 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362844 | Pre-made Rat Brd4 siRNA oligo Duplex | 362844 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo57261 | Pre-made Mouse Brd4/Brd5/MCAP siRNA oligo Duplex | 57261 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718195 | Pre-made Cynomolgus/Rhesus macaque BRD4 siRNA oligo Duplex | 718195 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100035 | Pre-made Cat/Feline BRD4 siRNA oligo Duplex | 101100035 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484869 | Pre-made Dog/Canine BRD4 siRNA oligo Duplex | 484869 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614048 | Pre-made Bovines/Cattle BRD4 siRNA oligo Duplex | 614048 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062072 | Pre-made Equine/Horse BRD4 siRNA oligo Duplex | 100062072 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BRD4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T40556-Ab | Human | Anti-Human BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T40556-Ab | Rat | Anti-Rat BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T40556-Ab | Mouse | Anti-Mouse BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T40556-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T40556-Ab | Cat/Feline | Anti-Cat/Feline BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T40556-Ab | Dog/Canine | Anti-Dog/Canine BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T40556-Ab | Bovines/Cattle | Anti-Bovines/Cattle BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T40556-Ab | Equine/Horse | Anti-Equine/Horse BRD4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
BRD4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T40556-Ag | Human | Human BRD4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T40556-Ag | Rat | Rat BRD4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T40556-Ag | Mouse | Mouse BRD4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T40556-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BRD4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T40556-Ag | Cat/Feline | Cat/Feline BRD4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T40556-Ag | Dog/Canine | Dog/Canine BRD4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T40556-Ag | Bovines/Cattle | Bovines/Cattle BRD4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T40556-Ag | Equine/Horse | Equine/Horse BRD4 recombinant protein | Mammalian cell | Detail |
