Recombinant multi-species EHMT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EHMT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
The Alternative Names of target: 9230102N17Rik,D330003E03,EHMT1,EHMT1-IT1,EUHMTASE1,Ehmt1,Eu-HMTase1,Euchromatic histone-lysine N-methyltransferase 1 (Eu-HMTase1),FP13812,G9a-like protein 1 (GLP,GLP,GLP1,GLP1),Histone H3-K9 methyltransferase 5 (H3-K9-HMTase 5),Histone-lysine N-methyltransferase EHMT1,KLEFS1,KMT1D,Lysine N-methyltransferase 1D,mKIAA1876
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T39996-Ag-1/ GM-Tg-hg-T39996-Ag-2 | Human EHMT1 protein | Human |
| GM-Tg-rg-T39996-Ag-1/ GM-Tg-rg-T39996-Ag-2 | Rat EHMT1 protein | Rat |
| GM-Tg-mg-T39996-Ag-1/ GM-Tg-mg-T39996-Ag-2 | Mouse EHMT1 protein | Mouse |
| GM-Tg-cynog-T39996-Ag-1/ GM-Tg-cynog-T39996-Ag-2 | Cynomolgus/Rhesus macaque EHMT1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T39996-Ag-1/ GM-Tg-felg-T39996-Ag-2 | Feline EHMT1 protein | Feline |
| GM-Tg-cang-T39996-Ag-1/ GM-Tg-cang-T39996-Ag-2 | Canine EHMT1 protein | Canine |
| GM-Tg-bovg-T39996-Ag-1/ GM-Tg-bovg-T39996-Ag-2 | Bovine EHMT1 protein | Bovine |
| GM-Tg-equg-T39996-Ag-1/ GM-Tg-equg-T39996-Ag-2 | Equine EHMT1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T39996-Ag-1/ GM-Tg-hg-T39996-Ag-2;
GM-Tg-rg-T39996-Ag-1/ GM-Tg-rg-T39996-Ag-2;
GM-Tg-mg-T39996-Ag-1/ GM-Tg-mg-T39996-Ag-2; GM-Tg-cynog-T39996-Ag-1/ GM-Tg-cynog-T39996-Ag-2; GM-Tg-felg-T39996-Ag-1/ GM-Tg-felg-T39996-Ag-2; GM-Tg-cang-T39996-Ag-1/ GM-Tg-cang-T39996-Ag-2; GM-Tg-bovg-T39996-Ag-1/ GM-Tg-bovg-T39996-Ag-2; GM-Tg-equg-T39996-Ag-1/ GM-Tg-equg-T39996-Ag-2 |
| Products Name | EHMT1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | EHMT1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EHMT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.