Explore EHMT1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T39996
|
| Target Name |
EHMT1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
79813
|
| Gene ID |
100058869 (Equus caballus), 101087111 (Felis catus), 362078 (Rattus norvegicus), 491224 (Canis lupus familiaris)
528606 (Bos taurus), 721470 (Macaca mulatta), 77683 (Mus musculus), 79813 (Homo sapiens)
|
| Target Alternative Names |
9230102N17Rik,D330003E03,EHMT1,EHMT1-IT1,EUHMTASE1,Ehmt1,Eu-HMTase1,Euchromatic histone-lysine N-methyltransferase 1 (Eu-HMTase1),FP13812,G9a-like protein 1 (GLP,GLP,GLP1,GLP1),Histone H3-K9 methyltransferase 5 (H3-K9-HMTase 5),Histone-lysine N-methyltransferase EHMT1,KLEFS1,KMT1D,Lysine N-methyltransferase 1D,mKIAA1876
|
| Uniprot Accession |
Q5DW34,Q9H9B1
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Longevity regulating pathway
|
| Gene Ensembl |
ENSECAG00000018405, ENSCAFG00845020437, ENSBTAG00000012148, ENSMMUG00000019613, ENSMUSG00000036893, ENSG00000181090
|
| Target Classification |
Epigenetic
|
Pre-made viral vector of EHMT1 cDNA Clones/ORF Plasmid
EHMT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo79813 | Pre-made Human EHMT1/GLP/GLP1 siRNA oligo Duplex | 79813 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362078 | Pre-made Rat Ehmt1 siRNA oligo Duplex | 362078 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo77683 | Pre-made Mouse Ehmt1/GLP/GLP1 siRNA oligo Duplex | 77683 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721470 | Pre-made Cynomolgus/Rhesus macaque EHMT1 siRNA oligo Duplex | 721470 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087111 | Pre-made Cat/Feline EHMT1 siRNA oligo Duplex | 101087111 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491224 | Pre-made Dog/Canine EHMT1 siRNA oligo Duplex | 491224 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528606 | Pre-made Bovines/Cattle EHMT1 siRNA oligo Duplex | 528606 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058869 | Pre-made Equine/Horse EHMT1 siRNA oligo Duplex | 100058869 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EHMT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T39996-Ab | Human | Anti-Human EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T39996-Ab | Rat | Anti-Rat EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T39996-Ab | Mouse | Anti-Mouse EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T39996-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T39996-Ab | Cat/Feline | Anti-Cat/Feline EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T39996-Ab | Dog/Canine | Anti-Dog/Canine EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T39996-Ab | Bovines/Cattle | Anti-Bovines/Cattle EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T39996-Ab | Equine/Horse | Anti-Equine/Horse EHMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
EHMT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T39996-Ag | Human | Human EHMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T39996-Ag | Rat | Rat EHMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T39996-Ag | Mouse | Mouse EHMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T39996-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EHMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T39996-Ag | Cat/Feline | Cat/Feline EHMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T39996-Ag | Dog/Canine | Dog/Canine EHMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T39996-Ag | Bovines/Cattle | Bovines/Cattle EHMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T39996-Ag | Equine/Horse | Equine/Horse EHMT1 recombinant protein | Mammalian cell | Detail |
