Recombinant multi-species TNKS/TNKS-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNKS/TNKS-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Enables histone binding activity; pentosyltransferase activity; and zinc ion binding activity. Involved in several processes, including negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric; protein ADP-ribosylation; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and protein ADP-ribosylation. Located in several cellular components, including chromosome, telomeric region; mitotic spindle pole; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
The Alternative Names of target: 4930554K12Rik,ADP-ribosyltransferase diphtheria toxin-like 5 (ARTD5),ARTD5,D130072O21Rik,PARP-5a,PARP5A,PARPL,Parp5a,Poly [ADP-ribose] polymerase 5A,Poly [ADP-ribose] polymerase tankyrase-1,Protein poly-ADP-ribosyltransferase tankyrase-1,TANK1,TIN1,TINF1,TNKS,TNKS-1,TNKS1,TRF1-interacting ankyrin-related ADP-ribose polymerase,Tankyrase I,Tankyrase-1 (TANK1),Tnks,mTNKS1,pART5

Target products collectionGo to TNKS/TNKS-1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T39231-Ag-1/ GM-Tg-hg-T39231-Ag-2 Human TNKS/TNKS-1 protein Human
GM-Tg-rg-T39231-Ag-1/ GM-Tg-rg-T39231-Ag-2 Rat TNKS/TNKS-1 protein Rat
GM-Tg-mg-T39231-Ag-1/ GM-Tg-mg-T39231-Ag-2 Mouse TNKS/TNKS-1 protein Mouse
GM-Tg-cynog-T39231-Ag-1/ GM-Tg-cynog-T39231-Ag-2 Cynomolgus/Rhesus macaque TNKS/TNKS-1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T39231-Ag-1/ GM-Tg-felg-T39231-Ag-2 Feline TNKS/TNKS-1 protein Feline
GM-Tg-cang-T39231-Ag-1/ GM-Tg-cang-T39231-Ag-2 Canine TNKS/TNKS-1 protein Canine
GM-Tg-bovg-T39231-Ag-1/ GM-Tg-bovg-T39231-Ag-2 Bovine TNKS/TNKS-1 protein Bovine
GM-Tg-equg-T39231-Ag-1/ GM-Tg-equg-T39231-Ag-2 Equine TNKS/TNKS-1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T39231-Ag-1/ GM-Tg-hg-T39231-Ag-2; GM-Tg-rg-T39231-Ag-1/ GM-Tg-rg-T39231-Ag-2;
GM-Tg-mg-T39231-Ag-1/ GM-Tg-mg-T39231-Ag-2; GM-Tg-cynog-T39231-Ag-1/ GM-Tg-cynog-T39231-Ag-2;
GM-Tg-felg-T39231-Ag-1/ GM-Tg-felg-T39231-Ag-2; GM-Tg-cang-T39231-Ag-1/ GM-Tg-cang-T39231-Ag-2;
GM-Tg-bovg-T39231-Ag-1/ GM-Tg-bovg-T39231-Ag-2; GM-Tg-equg-T39231-Ag-1/ GM-Tg-equg-T39231-Ag-2
Products Name TNKS/TNKS-1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TNKS/TNKS-1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNKS/TNKS-1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.