Explore TNKS/TNKS-1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Enables histone binding activity; pentosyltransferase activity; and zinc ion binding activity. Involved in several processes, including negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric; protein ADP-ribosylation; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and protein ADP-ribosylation. Located in several cellular components, including chromosome, telomeric region; mitotic spindle pole; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T39231
|
| Target Name |
TNKS/TNKS-1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8658
|
| Gene ID |
100058499 (Equus caballus), 101092933 (Felis catus), 21951 (Mus musculus), 290794 (Rattus norvegicus)
475603 (Canis lupus familiaris), 535030 (Bos taurus), 699004 (Macaca mulatta), 8658 (Homo sapiens)
|
| Target Alternative Names |
4930554K12Rik,ADP-ribosyltransferase diphtheria toxin-like 5 (ARTD5),ARTD5,D130072O21Rik,PARP-5a,PARP5A,PARPL,Parp5a,Poly [ADP-ribose] polymerase 5A,Poly [ADP-ribose] polymerase tankyrase-1,Protein poly-ADP-ribosyltransferase tankyrase-1,TANK1,TIN1,TINF1,TNKS,TNKS-1,TNKS1,TRF1-interacting ankyrin-related ADP-ribose polymerase,Tankyrase I,Tankyrase-1 (TANK1),Tnks,mTNKS1,pART5
|
| Uniprot Accession |
Q6PFX9,O95271
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000007431, ENSMUSG00000031529, ENSCAFG00845012924, ENSBTAG00000001463, ENSMMUG00000000965, ENSG00000173273
|
Pre-made viral vector of TNKS/TNKS-1 cDNA Clones/ORF Plasmid
TNKS/TNKS-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8658 | Pre-made Human TNKS/TIN1/ARTD5 siRNA oligo Duplex | 8658 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo290794 | Pre-made Rat Tnks siRNA oligo Duplex | 290794 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21951 | Pre-made Mouse Tnks/ARTD5/TANK1 siRNA oligo Duplex | 21951 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699004 | Pre-made Cynomolgus/Rhesus macaque TNKS siRNA oligo Duplex | 699004 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092933 | Pre-made Cat/Feline TNKS siRNA oligo Duplex | 101092933 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475603 | Pre-made Dog/Canine TNKS siRNA oligo Duplex | 475603 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535030 | Pre-made Bovines/Cattle TNKS siRNA oligo Duplex | 535030 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058499 | Pre-made Equine/Horse TNKS siRNA oligo Duplex | 100058499 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TNKS/TNKS-1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T39231-Ab | Human | Anti-Human TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T39231-Ab | Rat | Anti-Rat TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T39231-Ab | Mouse | Anti-Mouse TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T39231-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T39231-Ab | Cat/Feline | Anti-Cat/Feline TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T39231-Ab | Dog/Canine | Anti-Dog/Canine TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T39231-Ab | Bovines/Cattle | Anti-Bovines/Cattle TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T39231-Ab | Equine/Horse | Anti-Equine/Horse TNKS/TNKS-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
TNKS/TNKS-1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T39231-Ag | Human | Human TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T39231-Ag | Rat | Rat TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T39231-Ag | Mouse | Mouse TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T39231-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T39231-Ag | Cat/Feline | Cat/Feline TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T39231-Ag | Dog/Canine | Dog/Canine TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T39231-Ag | Bovines/Cattle | Bovines/Cattle TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T39231-Ag | Equine/Horse | Equine/Horse TNKS/TNKS-1 recombinant protein | Mammalian cell | Detail |
