Recombinant multi-species KLK14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
The Alternative Names of target: GK14,KLK-L6,KLK14,KLNM,Kallikrein-14,Kallikrein-like protein 6 (KLK-L6),Klk14,Klnm,hK14

Target products collectionGo to KLK14 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T39195-Ag-1/ GM-Tg-hg-T39195-Ag-2 Human KLK14 protein Human
GM-Tg-rg-T39195-Ag-1/ GM-Tg-rg-T39195-Ag-2 Rat KLK14 protein Rat
GM-Tg-mg-T39195-Ag-1/ GM-Tg-mg-T39195-Ag-2 Mouse KLK14 protein Mouse
GM-Tg-cynog-T39195-Ag-1/ GM-Tg-cynog-T39195-Ag-2 Cynomolgus/Rhesus macaque KLK14 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T39195-Ag-1/ GM-Tg-felg-T39195-Ag-2 Feline KLK14 protein Feline
GM-Tg-cang-T39195-Ag-1/ GM-Tg-cang-T39195-Ag-2 Canine KLK14 protein Canine
GM-Tg-bovg-T39195-Ag-1/ GM-Tg-bovg-T39195-Ag-2 Bovine KLK14 protein Bovine
GM-Tg-equg-T39195-Ag-1/ GM-Tg-equg-T39195-Ag-2 Equine KLK14 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T39195-Ag-1/ GM-Tg-hg-T39195-Ag-2; GM-Tg-rg-T39195-Ag-1/ GM-Tg-rg-T39195-Ag-2;
GM-Tg-mg-T39195-Ag-1/ GM-Tg-mg-T39195-Ag-2; GM-Tg-cynog-T39195-Ag-1/ GM-Tg-cynog-T39195-Ag-2;
GM-Tg-felg-T39195-Ag-1/ GM-Tg-felg-T39195-Ag-2; GM-Tg-cang-T39195-Ag-1/ GM-Tg-cang-T39195-Ag-2;
GM-Tg-bovg-T39195-Ag-1/ GM-Tg-bovg-T39195-Ag-2; GM-Tg-equg-T39195-Ag-1/ GM-Tg-equg-T39195-Ag-2
Products Name KLK14 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KLK14
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK14 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.