Explore KLK14 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
| Target ID |
GM-T39195
|
| Target Name |
KLK14
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
43847
|
| Gene ID |
100067040 (Equus caballus), 101097193 (Felis catus), 308562 (Rattus norvegicus), 317653 (Mus musculus) 43847 (Homo sapiens), 484348 (Canis lupus familiaris), 613993 (Bos taurus), 722692 (Macaca mulatta)
|
| Target Alternative Names |
GK14,KLK-L6,KLK14,KLNM,Kallikrein-14,Kallikrein-like protein 6 (KLK-L6),Klk14,Klnm,hK14
|
| Uniprot Accession |
Q8CGR5,Q9P0G3
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000015377, ENSMUSG00000044737, ENSG00000129437, ENSCAFG00845014650, ENSBTAG00000012538, ENSMMUG00000064856
|
Pre-made viral vector of KLK14 cDNA Clones/ORF Plasmid
KLK14 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo43847 | Pre-made Human KLK14/KLK-L6 siRNA oligo Duplex | 43847 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308562 | Pre-made Rat Klk14/Klnm siRNA oligo Duplex | 308562 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317653 | Pre-made Mouse Klk14/GK14 siRNA oligo Duplex | 317653 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722692 | Pre-made Cynomolgus/Rhesus macaque KLK14 siRNA oligo Duplex | 722692 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097193 | Pre-made Cat/Feline KLK14 siRNA oligo Duplex | 101097193 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484348 | Pre-made Dog/Canine KLK14 siRNA oligo Duplex | 484348 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613993 | Pre-made Bovines/Cattle KLK14 siRNA oligo Duplex | 613993 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067040 | Pre-made Equine/Horse KLK14/KLNM siRNA oligo Duplex | 100067040 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KLK14 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T39195-Ab | Human | Anti-Human KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T39195-Ab | Rat | Anti-Rat KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T39195-Ab | Mouse | Anti-Mouse KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T39195-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T39195-Ab | Cat/Feline | Anti-Cat/Feline KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T39195-Ab | Dog/Canine | Anti-Dog/Canine KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T39195-Ab | Bovines/Cattle | Anti-Bovines/Cattle KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T39195-Ab | Equine/Horse | Anti-Equine/Horse KLK14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KLK14 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T39195-Ag | Human | Human KLK14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T39195-Ag | Rat | Rat KLK14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T39195-Ag | Mouse | Mouse KLK14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T39195-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KLK14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T39195-Ag | Cat/Feline | Cat/Feline KLK14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T39195-Ag | Dog/Canine | Dog/Canine KLK14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T39195-Ag | Bovines/Cattle | Bovines/Cattle KLK14 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T39195-Ag | Equine/Horse | Equine/Horse KLK14 recombinant protein | Mammalian cell | Detail |