Recombinant multi-species KLK3/PSA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK3/PSA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]
The Alternative Names of target: APS,Gamma-seminoprotein (Seminin),KLK2A1,KLK3,Kallikrein-3,P-30 antigen,PSA,Prostate-specific antigen,Semenogelase,hK3

Target products collectionGo to KLK3/PSA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T36935-Ag-1/ GM-Tg-hg-T36935-Ag-2 Human KLK3/PSA protein Human
GM-Tg-rg-T36935-Ag-1/ GM-Tg-rg-T36935-Ag-2 Rat KLK3/PSA protein Rat
GM-Tg-mg-T36935-Ag-1/ GM-Tg-mg-T36935-Ag-2 Mouse KLK3/PSA protein Mouse
GM-Tg-cynog-T36935-Ag-1/ GM-Tg-cynog-T36935-Ag-2 Cynomolgus/Rhesus macaque KLK3/PSA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T36935-Ag-1/ GM-Tg-felg-T36935-Ag-2 Feline KLK3/PSA protein Feline
GM-Tg-cang-T36935-Ag-1/ GM-Tg-cang-T36935-Ag-2 Canine KLK3/PSA protein Canine
GM-Tg-bovg-T36935-Ag-1/ GM-Tg-bovg-T36935-Ag-2 Bovine KLK3/PSA protein Bovine
GM-Tg-equg-T36935-Ag-1/ GM-Tg-equg-T36935-Ag-2 Equine KLK3/PSA protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T36935-Ag-1/ GM-Tg-hg-T36935-Ag-2; GM-Tg-rg-T36935-Ag-1/ GM-Tg-rg-T36935-Ag-2;
GM-Tg-mg-T36935-Ag-1/ GM-Tg-mg-T36935-Ag-2; GM-Tg-cynog-T36935-Ag-1/ GM-Tg-cynog-T36935-Ag-2;
GM-Tg-felg-T36935-Ag-1/ GM-Tg-felg-T36935-Ag-2; GM-Tg-cang-T36935-Ag-1/ GM-Tg-cang-T36935-Ag-2;
GM-Tg-bovg-T36935-Ag-1/ GM-Tg-bovg-T36935-Ag-2; GM-Tg-equg-T36935-Ag-1/ GM-Tg-equg-T36935-Ag-2
Products Name KLK3/PSA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KLK3/PSA
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK3/PSA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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