Recombinant multi-species KLK3/PSA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK3/PSA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]
The Alternative Names of target: APS,Gamma-seminoprotein (Seminin),KLK2A1,KLK3,Kallikrein-3,P-30 antigen,PSA,Prostate-specific antigen,Semenogelase,hK3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T36935-Ag-1/ GM-Tg-hg-T36935-Ag-2 | Human KLK3/PSA protein | Human |
| GM-Tg-rg-T36935-Ag-1/ GM-Tg-rg-T36935-Ag-2 | Rat KLK3/PSA protein | Rat |
| GM-Tg-mg-T36935-Ag-1/ GM-Tg-mg-T36935-Ag-2 | Mouse KLK3/PSA protein | Mouse |
| GM-Tg-cynog-T36935-Ag-1/ GM-Tg-cynog-T36935-Ag-2 | Cynomolgus/Rhesus macaque KLK3/PSA protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T36935-Ag-1/ GM-Tg-felg-T36935-Ag-2 | Feline KLK3/PSA protein | Feline |
| GM-Tg-cang-T36935-Ag-1/ GM-Tg-cang-T36935-Ag-2 | Canine KLK3/PSA protein | Canine |
| GM-Tg-bovg-T36935-Ag-1/ GM-Tg-bovg-T36935-Ag-2 | Bovine KLK3/PSA protein | Bovine |
| GM-Tg-equg-T36935-Ag-1/ GM-Tg-equg-T36935-Ag-2 | Equine KLK3/PSA protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T36935-Ag-1/ GM-Tg-hg-T36935-Ag-2;
GM-Tg-rg-T36935-Ag-1/ GM-Tg-rg-T36935-Ag-2;
GM-Tg-mg-T36935-Ag-1/ GM-Tg-mg-T36935-Ag-2; GM-Tg-cynog-T36935-Ag-1/ GM-Tg-cynog-T36935-Ag-2; GM-Tg-felg-T36935-Ag-1/ GM-Tg-felg-T36935-Ag-2; GM-Tg-cang-T36935-Ag-1/ GM-Tg-cang-T36935-Ag-2; GM-Tg-bovg-T36935-Ag-1/ GM-Tg-bovg-T36935-Ag-2; GM-Tg-equg-T36935-Ag-1/ GM-Tg-equg-T36935-Ag-2 |
| Products Name | KLK3/PSA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | KLK3/PSA |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK3/PSA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.