KLK3/PSA Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore KLK3/PSA gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]

Target ID	GM-T36935
Target Name	KLK3/PSA
Gene Group ldentifer （Target Gene ID in Homo species)	354
Gene ID	354 (Homo sapiens)
Target Alternative Names	APS,Gamma-seminoprotein (Seminin),KLK2A1,KLK3,Kallikrein-3,P-30 antigen,PSA,Prostate-specific antigen,Semenogelase,hK3
Uniprot Accession	P07288
Protein Sub-location	Secreted Protein/Potential Cytokines
Category	Therapeutics Target, Immuno-oncology Target
Disease	cancer, Prostate Cancer, Malignant neoplasm of prostate
Disease from KEGG	Pathways in cancer, Prostate cancer
Gene Ensembl	ENSG00000142515
Target Classification	Checkpoint-Immuno Oncology

Pre-made viral vector of KLK3/PSA cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP000533	Human KLK3/APS/hK3 Lentivirus plasmid	NM_001648	354	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAP000060	Human KLK3/hK3/KLK2A1 Adenovirus plasmid	BC005307	354	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
pGMAP000250	Human KLK3/hK3/KLK2A1 Adenovirus plasmid	BC050595	354	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
vGMLP000533	Human KLK3/APS/hK3 Lentivirus particle	NM_001648	354	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAP000060	Human KLK3/hK3/KLK2A1 Adenovirus particle	BC005307	354	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
vGMAP000250	Human KLK3/hK3/KLK2A1 Adenovirus particle	BC050595	354	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail

KLK3/PSA siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo354	Pre-made Human KLK3/APS/PSA siRNA oligo Duplex	354	Human	In-vitro grade; in-vivo grade	Detail

KLK3/PSA antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T36935-Ab	Human	Anti-Human KLK3/PSA monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail

KLK3/PSA recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T36935-Ag	Human	Human KLK3/PSA recombinant protein	Mammalian cell	Detail