Recombinant multi-species ARG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Arginase catalyzes the hydrolysis of arginine to ornithine and urea.  At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function.  The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney.  The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism.  Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AII,ARG2,Arg2,Arginase II,Arginase-2,Kidney-type arginase,Non-hepatic arginase,Type II arginase,mitochondrial

Target products collectionGo to ARG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T36806-Ag-1/ GM-Tg-hg-T36806-Ag-2 Human ARG2 protein Human
GM-Tg-rg-T36806-Ag-1/ GM-Tg-rg-T36806-Ag-2 Rat ARG2 protein Rat
GM-Tg-mg-T36806-Ag-1/ GM-Tg-mg-T36806-Ag-2 Mouse ARG2 protein Mouse
GM-Tg-cynog-T36806-Ag-1/ GM-Tg-cynog-T36806-Ag-2 Cynomolgus/Rhesus macaque ARG2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T36806-Ag-1/ GM-Tg-felg-T36806-Ag-2 Feline ARG2 protein Feline
GM-Tg-cang-T36806-Ag-1/ GM-Tg-cang-T36806-Ag-2 Canine ARG2 protein Canine
GM-Tg-bovg-T36806-Ag-1/ GM-Tg-bovg-T36806-Ag-2 Bovine ARG2 protein Bovine
GM-Tg-equg-T36806-Ag-1/ GM-Tg-equg-T36806-Ag-2 Equine ARG2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T36806-Ag-1/ GM-Tg-hg-T36806-Ag-2; GM-Tg-rg-T36806-Ag-1/ GM-Tg-rg-T36806-Ag-2;
GM-Tg-mg-T36806-Ag-1/ GM-Tg-mg-T36806-Ag-2; GM-Tg-cynog-T36806-Ag-1/ GM-Tg-cynog-T36806-Ag-2;
GM-Tg-felg-T36806-Ag-1/ GM-Tg-felg-T36806-Ag-2; GM-Tg-cang-T36806-Ag-1/ GM-Tg-cang-T36806-Ag-2;
GM-Tg-bovg-T36806-Ag-1/ GM-Tg-bovg-T36806-Ag-2; GM-Tg-equg-T36806-Ag-1/ GM-Tg-equg-T36806-Ag-2
Products Name ARG2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ARG2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARG2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.