Explore ARG2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T36806
|
| Target Name |
ARG2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
384
|
| Gene ID |
100034051 (Equus caballus), 101092944 (Felis catus), 11847 (Mus musculus), 29215 (Rattus norvegicus) 384 (Homo sapiens), 480364 (Canis lupus familiaris), 518752 (Bos taurus), 711033 (Macaca mulatta)
|
| Target Alternative Names |
AII,ARG2,Arg2,Arginase II,Arginase-2,Kidney-type arginase,Non-hepatic arginase,Type II arginase,mitochondrial
|
| Uniprot Accession |
O08691,O08701,P78540,Q58DL1
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Amoebiasis
|
| Gene Ensembl |
ENSECAG00000016534, ENSMUSG00000021125, ENSG00000081181, ENSCAFG00845003478, ENSBTAG00000001945, ENSMMUG00000015865
|
Pre-made viral vector of ARG2 cDNA Clones/ORF Plasmid
ARG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo384 | Pre-made Human ARG2 siRNA oligo Duplex | 384 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29215 | Pre-made Rat Arg2 siRNA oligo Duplex | 29215 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11847 | Pre-made Mouse Arg2/AII siRNA oligo Duplex | 11847 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711033 | Pre-made Cynomolgus/Rhesus macaque ARG2 siRNA oligo Duplex | 711033 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092944 | Pre-made Cat/Feline ARG2 siRNA oligo Duplex | 101092944 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480364 | Pre-made Dog/Canine ARG2 siRNA oligo Duplex | 480364 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo518752 | Pre-made Bovines/Cattle ARG2 siRNA oligo Duplex | 518752 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034051 | Pre-made Equine/Horse ARG2 siRNA oligo Duplex | 100034051 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ARG2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T36806-Ab | Human | Anti-Human ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T36806-Ab | Rat | Anti-Rat ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T36806-Ab | Mouse | Anti-Mouse ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T36806-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T36806-Ab | Cat/Feline | Anti-Cat/Feline ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T36806-Ab | Dog/Canine | Anti-Dog/Canine ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T36806-Ab | Bovines/Cattle | Anti-Bovines/Cattle ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T36806-Ab | Equine/Horse | Anti-Equine/Horse ARG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ARG2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T36806-Ag | Human | Human ARG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T36806-Ag | Rat | Rat ARG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T36806-Ag | Mouse | Mouse ARG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T36806-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ARG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T36806-Ag | Cat/Feline | Cat/Feline ARG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T36806-Ag | Dog/Canine | Dog/Canine ARG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T36806-Ag | Bovines/Cattle | Bovines/Cattle ARG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T36806-Ag | Equine/Horse | Equine/Horse ARG2 recombinant protein | Mammalian cell | Detail |