Recombinant multi-species PPARD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPARD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]
The Alternative Names of target: FAAR,NR1C2,NUC-1,NUC1,NUCI,NUCII,Nr1c2,Nuclear hormone receptor 1 (NUC1),Nuclear receptor subfamily 1 group C member 2,PPAR-beta,PPAR-delta,PPARB,PPARD,PPAR[b],PPARdelta,Peroxisome proliferator-activated receptor beta (PPAR-beta),Peroxisome proliferator-activated receptor delta,Pparb,Pparb/d,Ppard

Target products collectionGo to PPARD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T36557-Ag-1/ GM-Tg-hg-T36557-Ag-2 Human PPARD protein Human
GM-Tg-rg-T36557-Ag-1/ GM-Tg-rg-T36557-Ag-2 Rat PPARD protein Rat
GM-Tg-mg-T36557-Ag-1/ GM-Tg-mg-T36557-Ag-2 Mouse PPARD protein Mouse
GM-Tg-cynog-T36557-Ag-1/ GM-Tg-cynog-T36557-Ag-2 Cynomolgus/Rhesus macaque PPARD protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T36557-Ag-1/ GM-Tg-felg-T36557-Ag-2 Feline PPARD protein Feline
GM-Tg-cang-T36557-Ag-1/ GM-Tg-cang-T36557-Ag-2 Canine PPARD protein Canine
GM-Tg-bovg-T36557-Ag-1/ GM-Tg-bovg-T36557-Ag-2 Bovine PPARD protein Bovine
GM-Tg-equg-T36557-Ag-1/ GM-Tg-equg-T36557-Ag-2 Equine PPARD protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T36557-Ag-1/ GM-Tg-hg-T36557-Ag-2; GM-Tg-rg-T36557-Ag-1/ GM-Tg-rg-T36557-Ag-2;
GM-Tg-mg-T36557-Ag-1/ GM-Tg-mg-T36557-Ag-2; GM-Tg-cynog-T36557-Ag-1/ GM-Tg-cynog-T36557-Ag-2;
GM-Tg-felg-T36557-Ag-1/ GM-Tg-felg-T36557-Ag-2; GM-Tg-cang-T36557-Ag-1/ GM-Tg-cang-T36557-Ag-2;
GM-Tg-bovg-T36557-Ag-1/ GM-Tg-bovg-T36557-Ag-2; GM-Tg-equg-T36557-Ag-1/ GM-Tg-equg-T36557-Ag-2
Products Name PPARD protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PPARD
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPARD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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