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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T36557
|
| Target Name |
PPARD
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5467
|
| Gene ID |
100053404 (Equus caballus), 101098383 (Felis catus), 19015 (Mus musculus), 25682 (Rattus norvegicus) 353106 (Bos taurus), 481756 (Canis lupus familiaris), 5467 (Homo sapiens), 718861 (Macaca mulatta)
|
| Target Alternative Names |
FAAR,NR1C2,NUC-1,NUC1,NUCI,NUCII,Nr1c2,Nuclear hormone receptor 1 (NUC1),Nuclear receptor subfamily 1 group C member 2,PPAR-beta,PPAR-delta,PPARB,PPARD,PPAR[b],PPARdelta,Peroxisome proliferator-activated receptor beta (PPAR-beta),Peroxisome proliferator-activated receptor delta,Pparb,Pparb/d,Ppard
|
| Uniprot Accession |
P35396,Q0ZAQ8,Q03181
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, IgA glomerulonephritis
|
| Disease from KEGG |
PPAR signaling pathway, Wnt signaling pathway, Pathways in cancer, Acute myeloid leukemia
|
| Gene Ensembl |
ENSECAG00000008227, ENSMUSG00000002250, ENSBTAG00000017542, ENSCAFG00845028955, ENSG00000112033, ENSMMUG00000015904
|
| Target Classification |
Nuclear Receptors
|
Pre-made viral vector of PPARD cDNA Clones/ORF Plasmid
PPARD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5467 | Pre-made Human PPARD/FAAR/NUC1 siRNA oligo Duplex | 5467 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25682 | Pre-made Rat Ppard/Pparb siRNA oligo Duplex | 25682 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19015 | Pre-made Mouse Ppard/NUC1/NUC-1 siRNA oligo Duplex | 19015 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718861 | Pre-made Cynomolgus/Rhesus macaque PPARD siRNA oligo Duplex | 718861 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098383 | Pre-made Cat/Feline PPARD siRNA oligo Duplex | 101098383 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481756 | Pre-made Dog/Canine PPARD/PPAR-beta/PPAR-delta siRNA oligo Duplex | 481756 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo353106 | Pre-made Bovines/Cattle PPARD/PPAR-beta siRNA oligo Duplex | 353106 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053404 | Pre-made Equine/Horse PPARD siRNA oligo Duplex | 100053404 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PPARD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T36557-Ab | Human | Anti-Human PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T36557-Ab | Rat | Anti-Rat PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T36557-Ab | Mouse | Anti-Mouse PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T36557-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T36557-Ab | Cat/Feline | Anti-Cat/Feline PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T36557-Ab | Dog/Canine | Anti-Dog/Canine PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T36557-Ab | Bovines/Cattle | Anti-Bovines/Cattle PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T36557-Ab | Equine/Horse | Anti-Equine/Horse PPARD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PPARD recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T36557-Ag | Human | Human PPARD recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T36557-Ag | Rat | Rat PPARD recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T36557-Ag | Mouse | Mouse PPARD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T36557-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PPARD recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T36557-Ag | Cat/Feline | Cat/Feline PPARD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T36557-Ag | Dog/Canine | Dog/Canine PPARD recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T36557-Ag | Bovines/Cattle | Bovines/Cattle PPARD recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T36557-Ag | Equine/Horse | Equine/Horse PPARD recombinant protein | Mammalian cell | Detail |