Recombinant multi-species MYC/c-MYC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYC/c-MYC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
The Alternative Names of target: C-MYC,CMYC,Class E basic helix-loop-helix protein 39 (bHLHe39),MRTL,MYC,MYCC,Myc,Myc proto-oncogene protein,Myc2,Niard,Nird,Proto-oncogene c-Myc,RNCMYC,Transcription factor p64,bHLHe39,c-MYC,c-Myc,c-myc,mMyc,v-myc

Target products collectionGo to MYC/c-MYC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T36121-Ag-1/ GM-Tg-hg-T36121-Ag-2 Human MYC/c-MYC protein Human
GM-Tg-rg-T36121-Ag-1/ GM-Tg-rg-T36121-Ag-2 Rat MYC/c-MYC protein Rat
GM-Tg-mg-T36121-Ag-1/ GM-Tg-mg-T36121-Ag-2 Mouse MYC/c-MYC protein Mouse
GM-Tg-cynog-T36121-Ag-1/ GM-Tg-cynog-T36121-Ag-2 Cynomolgus/Rhesus macaque MYC/c-MYC protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T36121-Ag-1/ GM-Tg-felg-T36121-Ag-2 Feline MYC/c-MYC protein Feline
GM-Tg-cang-T36121-Ag-1/ GM-Tg-cang-T36121-Ag-2 Canine MYC/c-MYC protein Canine
GM-Tg-bovg-T36121-Ag-1/ GM-Tg-bovg-T36121-Ag-2 Bovine MYC/c-MYC protein Bovine
GM-Tg-equg-T36121-Ag-1/ GM-Tg-equg-T36121-Ag-2 Equine MYC/c-MYC protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T36121-Ag-1/ GM-Tg-hg-T36121-Ag-2; GM-Tg-rg-T36121-Ag-1/ GM-Tg-rg-T36121-Ag-2;
GM-Tg-mg-T36121-Ag-1/ GM-Tg-mg-T36121-Ag-2; GM-Tg-cynog-T36121-Ag-1/ GM-Tg-cynog-T36121-Ag-2;
GM-Tg-felg-T36121-Ag-1/ GM-Tg-felg-T36121-Ag-2; GM-Tg-cang-T36121-Ag-1/ GM-Tg-cang-T36121-Ag-2;
GM-Tg-bovg-T36121-Ag-1/ GM-Tg-bovg-T36121-Ag-2; GM-Tg-equg-T36121-Ag-1/ GM-Tg-equg-T36121-Ag-2
Products Name MYC/c-MYC protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MYC/c-MYC
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYC/c-MYC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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