Recombinant multi-species ALOX12/12-LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOX12/12-LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
The Alternative Names of target: 12-LO,12-LOX,12S-LOX,12S-lipoxygenase),9930022G08Rik,ALOX12,Alox12,Alox12p,Arachidonate (12S)-lipoxygenase (12S-LOX,Arachidonate (15S)-lipoxygenase,LOG12,Linoleate (13S)-lipoxygenase,Lipoxin synthase 12-LO,P-12LO,Platelet-type lipoxygenase 12,Polyunsaturated fatty acid lipoxygenase ALOX12

Target products collectionGo to ALOX12/12-LOX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T35527-Ag-1/ GM-Tg-hg-T35527-Ag-2 Human ALOX12/12-LOX protein Human
GM-Tg-rg-T35527-Ag-1/ GM-Tg-rg-T35527-Ag-2 Rat ALOX12/12-LOX protein Rat
GM-Tg-mg-T35527-Ag-1/ GM-Tg-mg-T35527-Ag-2 Mouse ALOX12/12-LOX protein Mouse
GM-Tg-cynog-T35527-Ag-1/ GM-Tg-cynog-T35527-Ag-2 Cynomolgus/Rhesus macaque ALOX12/12-LOX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T35527-Ag-1/ GM-Tg-felg-T35527-Ag-2 Feline ALOX12/12-LOX protein Feline
GM-Tg-cang-T35527-Ag-1/ GM-Tg-cang-T35527-Ag-2 Canine ALOX12/12-LOX protein Canine
GM-Tg-bovg-T35527-Ag-1/ GM-Tg-bovg-T35527-Ag-2 Bovine ALOX12/12-LOX protein Bovine
GM-Tg-equg-T35527-Ag-1/ GM-Tg-equg-T35527-Ag-2 Equine ALOX12/12-LOX protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T35527-Ag-1/ GM-Tg-hg-T35527-Ag-2; GM-Tg-rg-T35527-Ag-1/ GM-Tg-rg-T35527-Ag-2;
GM-Tg-mg-T35527-Ag-1/ GM-Tg-mg-T35527-Ag-2; GM-Tg-cynog-T35527-Ag-1/ GM-Tg-cynog-T35527-Ag-2;
GM-Tg-felg-T35527-Ag-1/ GM-Tg-felg-T35527-Ag-2; GM-Tg-cang-T35527-Ag-1/ GM-Tg-cang-T35527-Ag-2;
GM-Tg-bovg-T35527-Ag-1/ GM-Tg-bovg-T35527-Ag-2; GM-Tg-equg-T35527-Ag-1/ GM-Tg-equg-T35527-Ag-2
Products Name ALOX12/12-LOX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ALOX12/12-LOX
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOX12/12-LOX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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