Explore ALOX12/12-LOX gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T35527
|
| Target Name |
ALOX12/12-LOX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
239
|
| Gene ID |
100072916 (Equus caballus), 11684 (Mus musculus), 239 (Homo sapiens), 287454 (Rattus norvegicus)
407169 (Bos taurus), 713748 (Macaca mulatta)
|
| Target Alternative Names |
12-LO,12-LOX,12S-LOX,12S-lipoxygenase),9930022G08Rik,ALOX12,Alox12,Alox12p,Arachidonate (12S)-lipoxygenase (12S-LOX,Arachidonate (15S)-lipoxygenase,LOG12,Linoleate (13S)-lipoxygenase,Lipoxin synthase 12-LO,P-12LO,Platelet-type lipoxygenase 12,Polyunsaturated fatty acid lipoxygenase ALOX12
|
| Uniprot Accession |
P39655,P18054,F1LQ70
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, Antifolate resistance, Serotonergic synapse, Inflammatory mediator regulation of TRP channels, Arachidonic acid metabolism
|
| Gene Ensembl |
ENSECAG00000022015, ENSMUSG00000000320, ENSG00000108839, ENSBTAG00000021933, ENSMMUG00000016264
|
| Target Classification |
|
ALOX12/12-LOX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo239 | Pre-made Human ALOX12/LOG12/12-LOX siRNA oligo Duplex | 239 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287454 | Pre-made Rat Alox12/12-LO/12S-LOX siRNA oligo Duplex | 287454 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11684 | Pre-made Mouse Alox12/P-12LO/Alox12p siRNA oligo Duplex | 11684 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713748 | Pre-made Cynomolgus/Rhesus macaque ALOX12 siRNA oligo Duplex | 713748 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407169 | Pre-made Bovines/Cattle ALOX12/12-LOX siRNA oligo Duplex | 407169 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072916 | Pre-made Equine/Horse ALOX12 siRNA oligo Duplex | 100072916 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ALOX12/12-LOX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T35527-Ab | Human | Anti-Human ALOX12/12-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T35527-Ab | Rat | Anti-Rat ALOX12/12-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T35527-Ab | Mouse | Anti-Mouse ALOX12/12-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T35527-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ALOX12/12-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T35527-Ab | Bovines/Cattle | Anti-Bovines/Cattle ALOX12/12-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T35527-Ab | Equine/Horse | Anti-Equine/Horse ALOX12/12-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ALOX12/12-LOX recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T35527-Ag | Human | Human ALOX12/12-LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T35527-Ag | Rat | Rat ALOX12/12-LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T35527-Ag | Mouse | Mouse ALOX12/12-LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T35527-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ALOX12/12-LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T35527-Ag | Bovines/Cattle | Bovines/Cattle ALOX12/12-LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T35527-Ag | Equine/Horse | Equine/Horse ALOX12/12-LOX recombinant protein | Mammalian cell | Detail |
