Recombinant multi-species SMAD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMAD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]
The Alternative Names of target: HSPC193,HsT17436,JV15-2,LDS1C,LDS3,MAD homolog 3,MADH3,Mad3,Madh3,Mothers against DPP homolog 3,Mothers against decapentaplegic homolog 3,SMAD family member 3 (SMAD 3,SMAD3,Smad 3,Smad3,hMAD-3,hSMAD3,hSMAD3),mad3

Target products collectionGo to SMAD3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T35445-Ag-1/ GM-Tg-hg-T35445-Ag-2 Human SMAD3 protein Human
GM-Tg-rg-T35445-Ag-1/ GM-Tg-rg-T35445-Ag-2 Rat SMAD3 protein Rat
GM-Tg-mg-T35445-Ag-1/ GM-Tg-mg-T35445-Ag-2 Mouse SMAD3 protein Mouse
GM-Tg-cynog-T35445-Ag-1/ GM-Tg-cynog-T35445-Ag-2 Cynomolgus/Rhesus macaque SMAD3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T35445-Ag-1/ GM-Tg-felg-T35445-Ag-2 Feline SMAD3 protein Feline
GM-Tg-cang-T35445-Ag-1/ GM-Tg-cang-T35445-Ag-2 Canine SMAD3 protein Canine
GM-Tg-bovg-T35445-Ag-1/ GM-Tg-bovg-T35445-Ag-2 Bovine SMAD3 protein Bovine
GM-Tg-equg-T35445-Ag-1/ GM-Tg-equg-T35445-Ag-2 Equine SMAD3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T35445-Ag-1/ GM-Tg-hg-T35445-Ag-2; GM-Tg-rg-T35445-Ag-1/ GM-Tg-rg-T35445-Ag-2;
GM-Tg-mg-T35445-Ag-1/ GM-Tg-mg-T35445-Ag-2; GM-Tg-cynog-T35445-Ag-1/ GM-Tg-cynog-T35445-Ag-2;
GM-Tg-felg-T35445-Ag-1/ GM-Tg-felg-T35445-Ag-2; GM-Tg-cang-T35445-Ag-1/ GM-Tg-cang-T35445-Ag-2;
GM-Tg-bovg-T35445-Ag-1/ GM-Tg-bovg-T35445-Ag-2; GM-Tg-equg-T35445-Ag-1/ GM-Tg-equg-T35445-Ag-2
Products Name SMAD3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SMAD3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMAD3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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