Recombinant multi-species cIAP2/BIRC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine cIAP2/BIRC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
The Alternative Names of target: AIP1,API2,Apoptosis inhibitor 2 (API2),BIRC2,BIRC3,Baculoviral IAP repeat-containing protein 3,CIAP2,Cellular inhibitor of apoptosis 2 (C-IAP2),HAIP1,HIAP1,IAP homolog C,IAP-1,Inhibitor of apoptosis protein 1 (hIAP-1,MALT2,MIHC,RING finger protein 49,RING-type E3 ubiquitin transferase BIRC3,RNF49,TNFR2-TRAF-signaling complex protein 1,c-IAP2,cIAP2,hIAP1)

Target products collectionGo to cIAP2/BIRC3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T35173-Ag-1/ GM-Tg-hg-T35173-Ag-2 Human cIAP2/BIRC3 protein Human
GM-Tg-rg-T35173-Ag-1/ GM-Tg-rg-T35173-Ag-2 Rat cIAP2/BIRC3 protein Rat
GM-Tg-mg-T35173-Ag-1/ GM-Tg-mg-T35173-Ag-2 Mouse cIAP2/BIRC3 protein Mouse
GM-Tg-cynog-T35173-Ag-1/ GM-Tg-cynog-T35173-Ag-2 Cynomolgus/Rhesus macaque cIAP2/BIRC3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T35173-Ag-1/ GM-Tg-felg-T35173-Ag-2 Feline cIAP2/BIRC3 protein Feline
GM-Tg-cang-T35173-Ag-1/ GM-Tg-cang-T35173-Ag-2 Canine cIAP2/BIRC3 protein Canine
GM-Tg-bovg-T35173-Ag-1/ GM-Tg-bovg-T35173-Ag-2 Bovine cIAP2/BIRC3 protein Bovine
GM-Tg-equg-T35173-Ag-1/ GM-Tg-equg-T35173-Ag-2 Equine cIAP2/BIRC3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T35173-Ag-1/ GM-Tg-hg-T35173-Ag-2; GM-Tg-rg-T35173-Ag-1/ GM-Tg-rg-T35173-Ag-2;
GM-Tg-mg-T35173-Ag-1/ GM-Tg-mg-T35173-Ag-2; GM-Tg-cynog-T35173-Ag-1/ GM-Tg-cynog-T35173-Ag-2;
GM-Tg-felg-T35173-Ag-1/ GM-Tg-felg-T35173-Ag-2; GM-Tg-cang-T35173-Ag-1/ GM-Tg-cang-T35173-Ag-2;
GM-Tg-bovg-T35173-Ag-1/ GM-Tg-bovg-T35173-Ag-2; GM-Tg-equg-T35173-Ag-1/ GM-Tg-equg-T35173-Ag-2
Products Name cIAP2/BIRC3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name cIAP2/BIRC3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine cIAP2/BIRC3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.