Recombinant multi-species AGR2/AG-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AGR2/AG-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
The Alternative Names of target: AG-2,AG2,AGR2,Agr2,Agr2h,Anterior gradient protein 2 homolog,GOB-4,Gob-4,HAG-2,HEL-S-116,HPC8,PDIA17,RIFTD,Secreted cement gland protein XAG-2 homolog,XAG-2,hAG-2,mAG-2

Target products collectionGo to AGR2/AG-2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T34352-Ag-1/ GM-Tg-hg-T34352-Ag-2 Human AGR2/AG-2 protein Human
GM-Tg-rg-T34352-Ag-1/ GM-Tg-rg-T34352-Ag-2 Rat AGR2/AG-2 protein Rat
GM-Tg-mg-T34352-Ag-1/ GM-Tg-mg-T34352-Ag-2 Mouse AGR2/AG-2 protein Mouse
GM-Tg-cynog-T34352-Ag-1/ GM-Tg-cynog-T34352-Ag-2 Cynomolgus/Rhesus macaque AGR2/AG-2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T34352-Ag-1/ GM-Tg-felg-T34352-Ag-2 Feline AGR2/AG-2 protein Feline
GM-Tg-cang-T34352-Ag-1/ GM-Tg-cang-T34352-Ag-2 Canine AGR2/AG-2 protein Canine
GM-Tg-bovg-T34352-Ag-1/ GM-Tg-bovg-T34352-Ag-2 Bovine AGR2/AG-2 protein Bovine
GM-Tg-equg-T34352-Ag-1/ GM-Tg-equg-T34352-Ag-2 Equine AGR2/AG-2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T34352-Ag-1/ GM-Tg-hg-T34352-Ag-2; GM-Tg-rg-T34352-Ag-1/ GM-Tg-rg-T34352-Ag-2;
GM-Tg-mg-T34352-Ag-1/ GM-Tg-mg-T34352-Ag-2; GM-Tg-cynog-T34352-Ag-1/ GM-Tg-cynog-T34352-Ag-2;
GM-Tg-felg-T34352-Ag-1/ GM-Tg-felg-T34352-Ag-2; GM-Tg-cang-T34352-Ag-1/ GM-Tg-cang-T34352-Ag-2;
GM-Tg-bovg-T34352-Ag-1/ GM-Tg-bovg-T34352-Ag-2; GM-Tg-equg-T34352-Ag-1/ GM-Tg-equg-T34352-Ag-2
Products Name AGR2/AG-2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AGR2/AG-2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AGR2/AG-2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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