Recombinant multi-species RGS6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RGS6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
The Alternative Names of target: GAP,HA117,RGS6,Regulator of G-protein signaling 6,Rgs6,S914
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T33909-Ag-1/ GM-Tg-hg-T33909-Ag-2 | Human RGS6 protein | Human |
GM-Tg-rg-T33909-Ag-1/ GM-Tg-rg-T33909-Ag-2 | Rat RGS6 protein | Rat |
GM-Tg-mg-T33909-Ag-1/ GM-Tg-mg-T33909-Ag-2 | Mouse RGS6 protein | Mouse |
GM-Tg-cynog-T33909-Ag-1/ GM-Tg-cynog-T33909-Ag-2 | Cynomolgus/Rhesus macaque RGS6 protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T33909-Ag-1/ GM-Tg-felg-T33909-Ag-2 | Feline RGS6 protein | Feline |
GM-Tg-cang-T33909-Ag-1/ GM-Tg-cang-T33909-Ag-2 | Canine RGS6 protein | Canine |
GM-Tg-bovg-T33909-Ag-1/ GM-Tg-bovg-T33909-Ag-2 | Bovine RGS6 protein | Bovine |
GM-Tg-equg-T33909-Ag-1/ GM-Tg-equg-T33909-Ag-2 | Equine RGS6 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T33909-Ag-1/ GM-Tg-hg-T33909-Ag-2;
GM-Tg-rg-T33909-Ag-1/ GM-Tg-rg-T33909-Ag-2;
GM-Tg-mg-T33909-Ag-1/ GM-Tg-mg-T33909-Ag-2; GM-Tg-cynog-T33909-Ag-1/ GM-Tg-cynog-T33909-Ag-2; GM-Tg-felg-T33909-Ag-1/ GM-Tg-felg-T33909-Ag-2; GM-Tg-cang-T33909-Ag-1/ GM-Tg-cang-T33909-Ag-2; GM-Tg-bovg-T33909-Ag-1/ GM-Tg-bovg-T33909-Ag-2; GM-Tg-equg-T33909-Ag-1/ GM-Tg-equg-T33909-Ag-2 |
Products Name | RGS6 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | RGS6 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RGS6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.