Explore RGS6 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
Target ID |
GM-T33909
|
Target Name |
RGS6
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9628
|
Gene ID |
100055109 (Equus caballus), 101083183 (Felis catus), 480380 (Canis lupus familiaris), 50779 (Mus musculus) 517545 (Bos taurus), 54295 (Rattus norvegicus), 694620 (Macaca mulatta), 9628 (Homo sapiens)
|
Target Alternative Names |
GAP,HA117,RGS6,Regulator of G-protein signaling 6,Rgs6,S914
|
Uniprot Accession |
Q9Z2H2,P49801,P49758
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000011760, ENSCAFG00845010233, ENSMUSG00000021219, ENSBTAG00000014189, ENSMMUG00000001820, ENSG00000182732
|
Target Classification |
|
Pre-made viral vector of RGS6 cDNA Clones/ORF Plasmid
RGS6 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo9628 | Pre-made Human RGS6/GAP/S914 siRNA oligo Duplex | 9628 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo54295 | Pre-made Rat Rgs6 siRNA oligo Duplex | 54295 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo50779 | Pre-made Mouse Rgs6 siRNA oligo Duplex | 50779 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo694620 | Pre-made Cynomolgus/Rhesus macaque RGS6 siRNA oligo Duplex | 694620 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101083183 | Pre-made Cat/Feline RGS6 siRNA oligo Duplex | 101083183 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo480380 | Pre-made Dog/Canine RGS6 siRNA oligo Duplex | 480380 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo517545 | Pre-made Bovines/Cattle RGS6 siRNA oligo Duplex | 517545 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100055109 | Pre-made Equine/Horse RGS6 siRNA oligo Duplex | 100055109 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RGS6 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T33909-Ab | Human | Anti-Human RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-T33909-Ab | Rat | Anti-Rat RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-T33909-Ab | Mouse | Anti-Mouse RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-T33909-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-T33909-Ab | Cat/Feline | Anti-Cat/Feline RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-T33909-Ab | Dog/Canine | Anti-Dog/Canine RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-T33909-Ab | Bovines/Cattle | Anti-Bovines/Cattle RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-T33909-Ab | Equine/Horse | Anti-Equine/Horse RGS6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RGS6 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T33909-Ag | Human | Human RGS6 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T33909-Ag | Rat | Rat RGS6 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T33909-Ag | Mouse | Mouse RGS6 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T33909-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RGS6 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T33909-Ag | Cat/Feline | Cat/Feline RGS6 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T33909-Ag | Dog/Canine | Dog/Canine RGS6 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T33909-Ag | Bovines/Cattle | Bovines/Cattle RGS6 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T33909-Ag | Equine/Horse | Equine/Horse RGS6 recombinant protein | Mammalian cell | Detail |