Recombinant multi-species MBL/MBL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MBL/MBL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jun 2020]
The Alternative Names of target: Ab2-001,Ab2-011,COLEC1,Collectin-1,HSMBPC,L-MBP,MBL,MBL-C,MBL1,MBL2,MBL2D,MBP,MBP-C,MBP1,MBPD,Mannan-binding protein,Mannose-binding lectin,Mannose-binding protein C,Mbl2,RARF/P28A

Target products collectionGo to MBL/MBL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T32699-Ag-1/ GM-Tg-hg-T32699-Ag-2 Human MBL/MBL2 protein Human
GM-Tg-rg-T32699-Ag-1/ GM-Tg-rg-T32699-Ag-2 Rat MBL/MBL2 protein Rat
GM-Tg-mg-T32699-Ag-1/ GM-Tg-mg-T32699-Ag-2 Mouse MBL/MBL2 protein Mouse
GM-Tg-cynog-T32699-Ag-1/ GM-Tg-cynog-T32699-Ag-2 Cynomolgus/Rhesus macaque MBL/MBL2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T32699-Ag-1/ GM-Tg-felg-T32699-Ag-2 Feline MBL/MBL2 protein Feline
GM-Tg-cang-T32699-Ag-1/ GM-Tg-cang-T32699-Ag-2 Canine MBL/MBL2 protein Canine
GM-Tg-bovg-T32699-Ag-1/ GM-Tg-bovg-T32699-Ag-2 Bovine MBL/MBL2 protein Bovine
GM-Tg-equg-T32699-Ag-1/ GM-Tg-equg-T32699-Ag-2 Equine MBL/MBL2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T32699-Ag-1/ GM-Tg-hg-T32699-Ag-2; GM-Tg-rg-T32699-Ag-1/ GM-Tg-rg-T32699-Ag-2;
GM-Tg-mg-T32699-Ag-1/ GM-Tg-mg-T32699-Ag-2; GM-Tg-cynog-T32699-Ag-1/ GM-Tg-cynog-T32699-Ag-2;
GM-Tg-felg-T32699-Ag-1/ GM-Tg-felg-T32699-Ag-2; GM-Tg-cang-T32699-Ag-1/ GM-Tg-cang-T32699-Ag-2;
GM-Tg-bovg-T32699-Ag-1/ GM-Tg-bovg-T32699-Ag-2; GM-Tg-equg-T32699-Ag-1/ GM-Tg-equg-T32699-Ag-2
Products Name MBL/MBL2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MBL/MBL2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MBL/MBL2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.