Recombinant multi-species HBB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HBB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Beta-globin,CD113t-C,ECYT6,HBB,Hbb,Hemoglobin beta chain,Hemoglobin subunit beta,beta-globin

Target products collectionGo to HBB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T31825-Ag-1/ GM-Tg-hg-T31825-Ag-2 Human HBB protein Human
GM-Tg-rg-T31825-Ag-1/ GM-Tg-rg-T31825-Ag-2 Rat HBB protein Rat
GM-Tg-mg-T31825-Ag-1/ GM-Tg-mg-T31825-Ag-2 Mouse HBB protein Mouse
GM-Tg-cynog-T31825-Ag-1/ GM-Tg-cynog-T31825-Ag-2 Cynomolgus/Rhesus macaque HBB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T31825-Ag-1/ GM-Tg-felg-T31825-Ag-2 Feline HBB protein Feline
GM-Tg-cang-T31825-Ag-1/ GM-Tg-cang-T31825-Ag-2 Canine HBB protein Canine
GM-Tg-bovg-T31825-Ag-1/ GM-Tg-bovg-T31825-Ag-2 Bovine HBB protein Bovine
GM-Tg-equg-T31825-Ag-1/ GM-Tg-equg-T31825-Ag-2 Equine HBB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T31825-Ag-1/ GM-Tg-hg-T31825-Ag-2; GM-Tg-rg-T31825-Ag-1/ GM-Tg-rg-T31825-Ag-2;
GM-Tg-mg-T31825-Ag-1/ GM-Tg-mg-T31825-Ag-2; GM-Tg-cynog-T31825-Ag-1/ GM-Tg-cynog-T31825-Ag-2;
GM-Tg-felg-T31825-Ag-1/ GM-Tg-felg-T31825-Ag-2; GM-Tg-cang-T31825-Ag-1/ GM-Tg-cang-T31825-Ag-2;
GM-Tg-bovg-T31825-Ag-1/ GM-Tg-bovg-T31825-Ag-2; GM-Tg-equg-T31825-Ag-1/ GM-Tg-equg-T31825-Ag-2
Products Name HBB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HBB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HBB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.