Recombinant multi-species PLA2G1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLA2G1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]
The Alternative Names of target: Group IB phospholipase A2,PLA2,PLA2A,PLA2G1B,PPLA2,Phosphatidylcholine 2-acylhydrolase 1B,Phospholipase A2,Pla2a,Pla2g1b,sPLA2IB

Target products collectionGo to PLA2G1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T31479-Ag-1/ GM-Tg-hg-T31479-Ag-2 Human PLA2G1B protein Human
GM-Tg-rg-T31479-Ag-1/ GM-Tg-rg-T31479-Ag-2 Rat PLA2G1B protein Rat
GM-Tg-mg-T31479-Ag-1/ GM-Tg-mg-T31479-Ag-2 Mouse PLA2G1B protein Mouse
GM-Tg-cynog-T31479-Ag-1/ GM-Tg-cynog-T31479-Ag-2 Cynomolgus/Rhesus macaque PLA2G1B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T31479-Ag-1/ GM-Tg-felg-T31479-Ag-2 Feline PLA2G1B protein Feline
GM-Tg-cang-T31479-Ag-1/ GM-Tg-cang-T31479-Ag-2 Canine PLA2G1B protein Canine
GM-Tg-bovg-T31479-Ag-1/ GM-Tg-bovg-T31479-Ag-2 Bovine PLA2G1B protein Bovine
GM-Tg-equg-T31479-Ag-1/ GM-Tg-equg-T31479-Ag-2 Equine PLA2G1B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T31479-Ag-1/ GM-Tg-hg-T31479-Ag-2; GM-Tg-rg-T31479-Ag-1/ GM-Tg-rg-T31479-Ag-2;
GM-Tg-mg-T31479-Ag-1/ GM-Tg-mg-T31479-Ag-2; GM-Tg-cynog-T31479-Ag-1/ GM-Tg-cynog-T31479-Ag-2;
GM-Tg-felg-T31479-Ag-1/ GM-Tg-felg-T31479-Ag-2; GM-Tg-cang-T31479-Ag-1/ GM-Tg-cang-T31479-Ag-2;
GM-Tg-bovg-T31479-Ag-1/ GM-Tg-bovg-T31479-Ag-2; GM-Tg-equg-T31479-Ag-1/ GM-Tg-equg-T31479-Ag-2
Products Name PLA2G1B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PLA2G1B
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLA2G1B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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