Explore PLA2G1B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]
| Target ID |
GM-T31479
|
| Target Name |
PLA2G1B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5319
|
| Gene ID |
100050467 (Equus caballus), 101095522 (Felis catus), 18778 (Mus musculus), 282457 (Bos taurus)
29526 (Rattus norvegicus), 404011 (Canis lupus familiaris), 5319 (Homo sapiens), 696712 (Macaca mulatta)
|
| Target Alternative Names |
Group IB phospholipase A2,PLA2,PLA2A,PLA2G1B,PPLA2,Phosphatidylcholine 2-acylhydrolase 1B,Phospholipase A2,Pla2a,Pla2g1b,sPLA2IB
|
| Uniprot Accession |
P00594,Q9Z0Y2,P00593,P04055,P06596,P04054
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Ras signaling pathway, Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism
|
| Gene Ensembl |
ENSECAG00000009152, ENSMUSG00000029522, ENSBTAG00000026732, ENSCAFG00845029696, ENSG00000170890, ENSMMUG00000031528
|
Pre-made viral vector of PLA2G1B cDNA Clones/ORF Plasmid
PLA2G1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5319 | Pre-made Human PLA2G1B/PLA2/PLA2A siRNA oligo Duplex | 5319 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29526 | Pre-made Rat Pla2g1b siRNA oligo Duplex | 29526 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18778 | Pre-made Mouse Pla2g1b/Pla2a/sPLA2IB siRNA oligo Duplex | 18778 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696712 | Pre-made Cynomolgus/Rhesus macaque PLA2G1B siRNA oligo Duplex | 696712 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095522 | Pre-made Cat/Feline PLA2G1B siRNA oligo Duplex | 101095522 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404011 | Pre-made Dog/Canine PLA2G1B siRNA oligo Duplex | 404011 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282457 | Pre-made Bovines/Cattle PLA2G1B siRNA oligo Duplex | 282457 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050467 | Pre-made Equine/Horse PLA2G1B siRNA oligo Duplex | 100050467 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PLA2G1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T31479-Ab | Human | Anti-Human PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T31479-Ab | Rat | Anti-Rat PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T31479-Ab | Mouse | Anti-Mouse PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T31479-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T31479-Ab | Cat/Feline | Anti-Cat/Feline PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T31479-Ab | Dog/Canine | Anti-Dog/Canine PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T31479-Ab | Bovines/Cattle | Anti-Bovines/Cattle PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T31479-Ab | Equine/Horse | Anti-Equine/Horse PLA2G1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PLA2G1B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T31479-Ag | Human | Human PLA2G1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T31479-Ag | Rat | Rat PLA2G1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T31479-Ag | Mouse | Mouse PLA2G1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T31479-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PLA2G1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T31479-Ag | Cat/Feline | Cat/Feline PLA2G1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T31479-Ag | Dog/Canine | Dog/Canine PLA2G1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T31479-Ag | Bovines/Cattle | Bovines/Cattle PLA2G1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T31479-Ag | Equine/Horse | Equine/Horse PLA2G1B recombinant protein | Mammalian cell | Detail |
