Recombinant multi-species TK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [provided by RefSeq, Oct 2016]
The Alternative Names of target: D530002A18Rik,TK1,TK2,Thymidine kinase,Tk,Tk-1,Tk1,Tk1a,Tk1b,cytosolic

Target products collectionGo to TK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T30081-Ag-1/ GM-Tg-hg-T30081-Ag-2 Human TK1 protein Human
GM-Tg-rg-T30081-Ag-1/ GM-Tg-rg-T30081-Ag-2 Rat TK1 protein Rat
GM-Tg-mg-T30081-Ag-1/ GM-Tg-mg-T30081-Ag-2 Mouse TK1 protein Mouse
GM-Tg-cynog-T30081-Ag-1/ GM-Tg-cynog-T30081-Ag-2 Cynomolgus/Rhesus macaque TK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T30081-Ag-1/ GM-Tg-felg-T30081-Ag-2 Feline TK1 protein Feline
GM-Tg-cang-T30081-Ag-1/ GM-Tg-cang-T30081-Ag-2 Canine TK1 protein Canine
GM-Tg-bovg-T30081-Ag-1/ GM-Tg-bovg-T30081-Ag-2 Bovine TK1 protein Bovine
GM-Tg-equg-T30081-Ag-1/ GM-Tg-equg-T30081-Ag-2 Equine TK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T30081-Ag-1/ GM-Tg-hg-T30081-Ag-2; GM-Tg-rg-T30081-Ag-1/ GM-Tg-rg-T30081-Ag-2;
GM-Tg-mg-T30081-Ag-1/ GM-Tg-mg-T30081-Ag-2; GM-Tg-cynog-T30081-Ag-1/ GM-Tg-cynog-T30081-Ag-2;
GM-Tg-felg-T30081-Ag-1/ GM-Tg-felg-T30081-Ag-2; GM-Tg-cang-T30081-Ag-1/ GM-Tg-cang-T30081-Ag-2;
GM-Tg-bovg-T30081-Ag-1/ GM-Tg-bovg-T30081-Ag-2; GM-Tg-equg-T30081-Ag-1/ GM-Tg-equg-T30081-Ag-2
Products Name TK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.