Recombinant multi-species LIF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LIF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
The Alternative Names of target: CDF,DIA,Differentiation-stimulating factor (D factor),HILDA,LIF,Leukemia inhibitory factor,Lif,MLPLI,Melanoma-derived LPL inhibitor (MLPLI)

Target products collectionGo to LIF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T29774-Ag-1/ GM-Tg-hg-T29774-Ag-2 Human LIF protein Human
GM-Tg-rg-T29774-Ag-1/ GM-Tg-rg-T29774-Ag-2 Rat LIF protein Rat
GM-Tg-mg-T29774-Ag-1/ GM-Tg-mg-T29774-Ag-2 Mouse LIF protein Mouse
GM-Tg-cynog-T29774-Ag-1/ GM-Tg-cynog-T29774-Ag-2 Cynomolgus/Rhesus macaque LIF protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T29774-Ag-1/ GM-Tg-felg-T29774-Ag-2 Feline LIF protein Feline
GM-Tg-cang-T29774-Ag-1/ GM-Tg-cang-T29774-Ag-2 Canine LIF protein Canine
GM-Tg-bovg-T29774-Ag-1/ GM-Tg-bovg-T29774-Ag-2 Bovine LIF protein Bovine
GM-Tg-equg-T29774-Ag-1/ GM-Tg-equg-T29774-Ag-2 Equine LIF protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T29774-Ag-1/ GM-Tg-hg-T29774-Ag-2; GM-Tg-rg-T29774-Ag-1/ GM-Tg-rg-T29774-Ag-2;
GM-Tg-mg-T29774-Ag-1/ GM-Tg-mg-T29774-Ag-2; GM-Tg-cynog-T29774-Ag-1/ GM-Tg-cynog-T29774-Ag-2;
GM-Tg-felg-T29774-Ag-1/ GM-Tg-felg-T29774-Ag-2; GM-Tg-cang-T29774-Ag-1/ GM-Tg-cang-T29774-Ag-2;
GM-Tg-bovg-T29774-Ag-1/ GM-Tg-bovg-T29774-Ag-2; GM-Tg-equg-T29774-Ag-1/ GM-Tg-equg-T29774-Ag-2
Products Name LIF protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LIF
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LIF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.